Pathways in pathogenesis of PAH – Cardiology MCQ – Answer
Pathways in pathogenesis of PAH – Cardiology MCQ – Answer
Which of the following is NOT a pathway involved in the pathogenesis of pulmonary arterial hypertension (PAH)?
Correct answer: 4. Pentose phosphate pathway
All the other three are important pathways in the pathogenesis of PAH. Medications used in the treatment block these pathways.
Endothelin pathway blockers: Bosentan, Ambrisentan, Macitentan
Nitric oxide pathway: Sildenafil, Tadalafil, Vardenafil
Prostacyclin pathway: Epoprostenol, Iloprost, Treprostinil, Beraprost (Prostacyclin analogues) and Selexipag (Selective IP receptor antagonist). IP receptor is short for Prostaglandin I2 receptor or prostacyclin receptor.
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Source: Cardiophile MD - Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs