Long-term exposure to fluoride as a factor promoting changes in the expression and activity of cyclooxygenases (COX1 and COX2) in various rat brain structures.

CONCLUSION: Exposure to fluoride in the prenatal and neonatal period result in the increase in COX2 activity and increase in PGE2 concentration in rats brain, which may lead to disturbances in central nervous system homeostasis.‬‬. PMID: 31175943 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31175943?dopt=Abstract

Source: Neurotoxicology - June 4, 2019 Category: Neurology Authors: Dec K, Łukomska A, Skonieczna-Żydecka K, Kolasa-Wołosiuk A, Tarnowski M, Baranowska-Bosiacka I, Gutowska I Tags: Neurotoxicology Source Type: research