Folate as an Adjuvant Therapy in Methanol Poisoning.

Folate as an Adjuvant Therapy in Methanol Poisoning. Nutr Clin Pract. 2019 Jun 06;: Authors: Theobald J, Lim C Abstract Folate and its derivatives have long been used as an adjunctive treatment in methanol poisoning. Methanol is ultimately metabolized to formate, the toxic compound. The accumulation of formate can lead to acidemia, retinal damage, visual impairment, and death. Formate is converted to carbon dioxide and water in a folate-dependent manner, and folate is often given in cases of methanol poisoning. In this paper, the evidence for folate as an adjunctive therapy in methanol poisoning is reviewed. PMID: 31172585 [PubMed - as supplied by publisher]
Source: Nutrition in Clinical Practice - Category: Nutrition Authors: Tags: Nutr Clin Pract Source Type: research