Migraine comorbidity and cognitive performance in patients with focal epilepsy

ConclusionIn this study, there was no association between migraine comorbidity and objective cognitive scores in patients with newly diagnosed focal epilepsy. The relationship between migraine comorbidity and subjective memory deficits seemed to be mediated by the higher prevalence of depression and anxiety symptoms in patients with epilepsy with comorbid migraine.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

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Publication date: Available online 25 January 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): H. Saghafi, P. Benington, A. AyoubAbstractThe aim of this study was to compare the impact that the orthodontics-first approach and the surgery-first approach have on quality of life, anxiety, and depression in patients treated for dentofacial deformities. Data were collected on 32 patients (aged 17–47 years) who were all treated at a single multidisciplinary orthognathic clinic. They completed a 22-item Orthognathic Quality of Life Questionnaire (OQLQ), a seven-item Generalised Anxiety Disorder (GAD-7...
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 25 January 2020Source: Pharmacology &TherapeuticsAuthor(s): Yun-Feng LiAbstractMajor depressive disorder has become a global public health problem of serious concern. Most of the clinical antidepressants are developed under the classic “monoamine hypothesis (strategy)”. These drugs generally have such deficiencies including slow onset and limited efficiency, cognitive impairment and suicidal tendency. Therefore, it is the direction to break through the classic monoamine strategy framework for developing antidepressants that have fast-acting, lower side effects, and cogniti...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
ConclusionsThe results suggested that KXS exerted antidepressant effects by regulating the signaling pathways involved in lipid metabolism disorders. The lipid metabolites might be potential biomarkers of depression and possible targets for KXS-based treatment of depression.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
CONCLUSION: In this study, there was no association between migraine comorbidity and objective cognitive scores in patients with newly diagnosed focal epilepsy. The relationship between migraine comorbidity and subjective memory deficits seemed to be mediated by the higher prevalence of depression and anxiety symptoms in patients with epilepsy with comorbid migraine. PMID: 31181426 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Conclusion: Our results indicate similar prevalence rates of comorbid psychiatric symptoms to studies carried out in the Middle East and North Africa (MENA) region and relatively high attendance and referral rates to psychiatric services.Implications: The results shed light on the clinical profile of patients in this region and support the need for integrated collaborative medical services. Moreover, findings have important implications for health care policies pertaining to resource distribution and funding.IntroductionMedical care has traditionally been dominated by a separation between disciplines catering to physiologi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is prema...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
According to this study, CBD causes hormonal changes that can lessen the intensity of anxiety disorders including generalized anxiety disorder, PTSD, and social anxiety. Regulates Behaviour &Cognition CBD interacts with a broad range of receptors, and through complicated processes, it works as a therapeutic agent. While behavioral patterns tend to be complicated for many people, there are ways that CBD can reduce destructive behavior and facilitate positive change. For instance, addiction is one of the areas that lead to unproductive behavioral patterns, and CBD has been used successfully to treat different forms of ad...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness self improvement brain cbd oil pickthebrain Source Type: blogs
Conclusions: The NLEM group has economical drugs in some disease categories; there is a need to consider the cost effectiveness of all drug categories while revising the NLEM next time and attention should focus on drug price regulation policies to accomplish the goal of rational use of medicines.
Source: Neurology India - Category: Neurology Authors: Source Type: research
Conclusions:This post hoc analysis indicated that lacosamide monotherapy was efficacious and generally well tolerated in patients with newly-diagnosed epilepsy and psychiatric comorbidities.Study Supported by: UCB PharmaDisclosure: Dr. Schmitz received personal compensation for activities with UCB Pharma, Desitin Pharma, and Eisai as a speaker. Dr. Schmitz received research support from UCB Pharma. Dr. Newton has nothing to disclose. Dr. Dimova has received personal compensation for activities with UCB Pharma as an employee. Dr. Dimova holds stock and/or stock options in UCB Pharma. Dr. Zhang has received personal compensa...
Source: Neurology - Category: Neurology Authors: Tags: Epilepsy and Clinical Neurophysiology: Clinical Epilepsy IV Source Type: research
Conclusion Findings from this study provide extensive information on clinical characteristics and utilization of AEDs in Chinese patients with epilepsy which may help physicians make well-informed clinical decisions.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
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