Brucea javanica oil emulsion improves the effect of radiotherapy on esophageal cancer cells by inhibiting cyclin D1-CDK4/6 axis.

CONCLUSION: BJOE has a strong anti-cancer effect on esophageal cancer and can be used as a radiosensitizer to promote apoptosis in cancerous esophageal cells via the cyclin D1-cyclin-dependent kinase 4/6 axis.
PMID: 31171890 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - May 27, 2019 Category: Gastroenterology Authors: Qiu ZH, Zhang WW, Zhang HH, Jiao GH Tags: World J Gastroenterol Source Type: research