Interleukin-22 receptor 1 is expressed in multinucleated giant cells: A study on intestinal tuberculosis and Crohn's disease.

CONCLUSION: High IL-22 expression seems to be a protective factor for intestinal tuberculosis. IL-22R1 is expressed in Langhans giant cells, suggesting that the IL-22/IL-22R1 system links adaptive and innate immunity.
PMID: 31171891 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - May 27, 2019 Category: Gastroenterology Authors: Yu ZQ, Wang WF, Dai YC, Chen XC, Chen JY Tags: World J Gastroenterol Source Type: research