Revisiting the synthesis of trans-[Pt(dmso)2ClMe] and cis-[Pt(dmso)2Me2]: Experimental and DFT studies

Publication date: Available online 7 June 2019Source: Journal of Organometallic ChemistryAuthor(s): Edwin A. Baquero, Ana Rodríguez-Zúñiga, Juan C. Flores, Manuel Temprado, Ernesto de JesúsAbstractThe preparation of trans-[Pt(dmso)2ClMe] (2) and cis-[Pt(dmso)2Me2] (3) from cis-[Pt(dmso)2Cl2] (1) and SnMe4 has been reexamined (dmso = dimethyl sulfoxide). The information obtained from experimental and DFT studies has permitted the improvement of previously reported methods for the synthesis of both complexes in terms of reaction times, reaction yields, and atom economy. These studies show that complex 1 reacts with a first equiv of SnMe4 to form trans-[Pt(dmso)2ClMe] (2) as an intermediate that quickly reacts with a second equiv of SnMe4 to yield cis-[Pt(dmso)2Me2] (3). When only 1 equiv of the organostannane reagent is added, the comproportionation of 3 with the excess of unreacted 1 leads the reaction back to the formation of trans-[Pt(dmso)2ClMe] (2). The mechanism of this comproportionation has been studied using DFT calculations.Graphical abstract

Source: Journal of Organometallic Chemistry - June 8, 2019 Category: Chemistry Source Type: research