Atherosclerotic cardiovascular disease in women with endometriosis: A critical review of risk factors and prospects for early surveillance
Publication date: Available online 8 June 2019Source: Reproductive BioMedicine OnlineAuthor(s): Justin Tan, Omur Taskin, Mahmoud Iews, Arthur J Lee, Arohumam Kan, Timothy Rowe, Mohamed A. BedaiwyABSTRACTEndometriosis and atherosclerotic cardiovascular disease (ASCVD) share similar pathogenic mechanisms. Hence, this systematic review evaluates the association between endometriosis and lifetime ASCVD risk including co-prevalence with dyslipidemia, atherosclerosis, and non-invasive markers of endothelial dysfunction. Among 12 studies (401 patients with surgically proven endometriosis and 557 controls), two prospective-cohort studies demonstrated an increased lifetime ASCVD risk after controlling for demographic and lifestyle confounders in women with endometriosis, as measured by higher incidence of myocardial infarction, angiography-confirmed angina, or requiring coronary artery bypass graft surgery (RR1.35-1.62). Relative risks of developing hypercholesterolemia and hypertension were 1.25 and 1.14, respectively, which are supported by other studies that demonstrate higher serum Lp(a) and lower PON-1 levels in women with endometriosis that was negatively correlated with stage of disease (r=−0.74, P
The aim of this study is to assess whether the use of MRI as part of preoperative workup in the setting of patients with chronic pelvic pain and presumed diagnosis of endometriosis is predictive of pathology-proven endometriosis.
The purpose of this study is to describe the rate of appendiceal endometriosis (AppE) in women having coincidental appendectomy at time of gynecologic surgery for pelvic pain, stage I-II endometriosis, or stage III-IV endometriosis. Coincidental appendectomy as standard of care in surgery for endometriosis and chronic pelvic pain has not been widely adopted largely due to uncertainty as to the prevalence of appendiceal pathology and procedure safety.
The objective of this study was to review patient characteristics, preoperative and intraoperative findings for excised cases of rectus muscle endometriosis.
Endometriosis is a prevalent disease associated with significant cost; over $49 billion in medical costs is spent annually in the United States (US) alone. Limited data exist on the cost-effectiveness of various clinical regimens to guide management. We sought to determine which sequence of therapies would be most cost-effective for the treatment of endometriosis-related pain.
The objectives of this video are to review indications for pelvic peritonectomy, discuss preoperative set up, and demonstrate our technique of complete pelvic peritonectomy.
The goal of this video is to highlight the relevant anatomy for the surgical management of diaphragmatic endometriosis as well as tips and tricks that may be helpful for surgeons to implement during these procedures.
The objective of this study was to describe the perioperative morbidity of patients with class III morbid obesity undergoing hysterectomy form benign disease.
The purpose of this video is to describe the vaginal appendectomy (VagAppy), a novel approach to coincidental appendectomy at time of hysterectomy. Coincidental appendectomy at time of a primary gynecologic procedure has been described in the literature for many years. There is a growing body of evidence supporting appendectomy as part of surgical management of endometriosis given the prevalence of appendiceal endometriosis, as high as 39% in deep infiltrating endometriosis. A common technique for performance of a laparoscopic appendectomy is with a surgical stapler.
(CNN) — Google users in the United States had a lot of questions about blood pressure, the keto diet and hiccups in 2019. Those topics were among the 10 most-searched health-related questions on the search engine this year, according to new data from Google. The list was based on search terms collected between January and early December. Last year, the top health-related questions Googled by people in the US included what is amyotrophic lateral sclerosis, or ALS, what is endometriosis and how long does weed stay in your urine. In 2017, what is lupus, how long does the flu last and what causes hiccups were some of the...
Publication date: Available online 8 June 2019Source: Reproductive BioMedicine OnlineAuthor(s): Justin Tan, Omur Taskin, Mahmoud Iews, Arthur J Lee, Arohumam Kan, Timothy Rowe, Mohamed A BedaiwyAbstractEndometriosis and atherosclerotic cardiovascular disease (ASCVD) share similar pathogenic mechanisms. Hence, this systematic review evaluates the association between endometriosis and lifetime ASCVD risk including co-prevalence with dyslipidaemia, atherosclerosis and non-invasive markers of endothelial dysfunction. The electronic databases Embase, PubMed, MEDLINE, Cochrane Register of Trials and ClinicalTrials.gov were syste...