Development of a program theory for clinical pathways in hospitals: protocol for a realist review

The objective of this realist review is to develop a program theory for CPWs in hospitals.MethodsThis is a protocol for a realist review. The review will use a six-step iterative process to develop a program theory for CPWs in hospitals: (1) development of a preliminary program theory; (2) search strategy and literature search; (3) study selection and appraisal; (4) data extraction; (5) data analysis and synthesis; and (6) stakeholder engagement. In addition to searching the gray literature and contacting authors, we will search electronic databases such as MEDLINE, NHSEED, CINAHL EBSCO, HMIC, and PsycINFO. Studies will be included based on their ability to provide data that test some aspect of the program theory. Two independent reviewers will select, screen, and extract data related to the program theory from all relevant sources. A realist logic of analysis will be used to identify all context-mechanism-outcome heuristics that explains how CPWs implemented in hospitals translates to better health system outcomes.DiscussionOverall, the review aims to develop a program theory for CPWs in hospitals and to explore how, why, to what extent, and in what contexts does the implementation of CPWs in hospitals contribute to better health system outcomes. As a result, the review will provide a theoretical framework of how CPWs work in hospitals.Systematic review registrationPROSPEROCRD42018103220
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research

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Publication date: Available online 17 July 2019Source: Journal of Integrative MedicineAuthor(s): Pierre Watcho, Ismaelle Rosine Mpeck, Patrick Brice Defo Deeh, Modeste W.eu-Nya, Esther Ngadjui, Georges Romeo Fozin Bonsou, Pierre Kamtchouing, Albert KamanyiAbstractObjectiveCyclophosphamide (CP) is commonly used to treat some cancers, but its clinical efficacy is also linked with testicular toxicity. We investigated the effects of aqueous extract (AE) and methanolic extract (ME) of Helichrysum odoratissimum for reducing CP-induced reproductive toxicity in male rats.MethodsIn addition to a normal control (group 1), drugs or v...
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
This study used Oswestry Disability Index (ODI)-self-comparison and showed that acupuncture treatments for lumber disc herniation and sciatica demonstrated significant improvement in long term clinical outcomes. A total of 112 lumbar disc herniation and sciatica cases were treated with electric acupuncture for pain relief and function improvement from July 1998 to December 2006.ResultsAll the 112 cases filled out the ODI forms prior to receiving treatment. Among the 112 patients, 23 of them did not finish the 6-week treatments. 89 cases were evaluated with ODI after 6-week acupuncture treatments. Of those 89 cases, 67 case...
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research
ConclusionsThe therapeutic effect of acupuncture and moxibustion by soothing liver and regulating mind can obviously improve the quality of life of depression elders.
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research
ConclusionRV Dysfunction according to our definition in first Anterior MI occurred in (55%) of the study population. Independent predictors for Abnormal RV function were; LCX mid or proximal affection, eventful procedure, occurrence of no reflow, Glucose level, LVESD, LVEDD and LV EF.
Source: Journal of the Saudi Heart Association - Category: Cardiology Source Type: research
Publication date: Available online 17 July 2019Source: Global HeartAuthor(s): Jessica Ying-Yi Xie, Matthew R. Solomons, Mahmood Ahmad
Source: Global Heart - Category: Cardiology Source Type: research
Publication date: Available online 18 July 2019Source: American Heart JournalAuthor(s): Nwora Lance Okeke, Allison R. Webel, Hayden B. Bosworth, Angela Aifa, Gerald S. Bloomfield, Emily Choi, Sarah Gonzales, Sarah Hale, Corrilynn O. Hileman, Virginia Kidwell, Charles Muiruri, Megan Oakes, Julie Schexnayder, Valerie Smith, Rajesh Vedanthan, Chris T. Longenecker
Source: American Heart Journal - Category: Cardiology Source Type: research
Conclusion: Experiences of being sexually harassed correlate among adolescents with high social anxiety but also with high self-esteem. Sexual harassment among adolescents may partly be explained as inept ways of showing interest, but it may nevertheless have detrimental effects on the well-being of the those subjected to it. PMID: 31311376 [PubMed - as supplied by publisher]
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Geriatric OncologyAuthor(s): Mina S. Sedrak, Daneng Li, Louise C. Walter, Karen Mustian, Kevin P. High, Beverly Canin, Supriya G. Mohile, William Dale, Can-Lan Sun
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Geriatric OncologyAuthor(s): Melisa L. Wong, Stuart M. Lichtman, Gary R. Morrow, John Simmons, Tomma Hargraves, Cary P. Gross, Jennifer L. Lund, Lisa M. Lowenstein, Louise C. Walter, Cara L. McDermott, Supriya G. Mohile, Harvey Jay Cohen
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
ConclusionIn a cohort of 40 older adults with newly diagnosed multiple myeloma, three frailty indices have differing approaches to operationalizing frailty resulting, in different patients being categorized as frail. Little agreement existed between the models. Further studies are needed to explore the utility of these models in predicting treatment toxicity and prognosis.
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
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