Irritable Bowel Symptoms Tied to Intestinal, Brain Abnormalities

FRIDAY, June 7, 2019 -- A greater number of intestinal and brain function abnormalities increases the burden of irritable bowel syndrome (IBS), according to a study recently published in Gastroenterology. Magnus Simr én, M.D., Ph.D., from the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Functional dyspepsia (FD), belching disorders (BD) and functional heartburn (FH) are the three most common upper functional gastrointestinal disorders (FGID) in IBS patients. FD is known to exert deleterious e...
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Tags: Research article Source Type: research
Conclusion: Electroacupuncture alleviates IBS visceral hypersensitivity by inhibiting the activation of astrocytes in the MT and ACC. PMID: 32617101 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
ConclusionsAnti-IBS syrup significantly reduced the severity of IBS symptoms compared to placebo. However, there was a need for further investigation regarding the anxiety and depression scores. (Registration No. IRCT2017061034446N1).
Source: Chinese Journal of Integrative Medicine - Category: Internal Medicine Source Type: research
Conclusion: The prevalence and risk factors of migraine headache in Arab countries are comparable to reports from western countries. Longitudinal studies are still needed to investigate the prognosis and predictors of chronicity in the arab countries. PMID: 32607079 [PubMed - in process]
Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
Condition:   Non-erosive Reflux Disease/Diarrheal Irritable Bowel Syndrome Interventions:   Drug: tong-jiang granules;   Drug: Chang 'an II Recipe;   Drug: The placebo of tong-jiang granules;   Drug: The placebo of Chang 'an II Recipe Sponsor:   Xiyuan Hospital of China Academy of Chinese Medical Sciences Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Clinical and Experimental Gastroenterology - Category: Gastroenterology Tags: Clinical and Experimental Gastroenterology Source Type: research
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits. Leading to signi...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
AbstractFecal microbiota transplantation (FMT) has demonstrated efficacy in treating inflammatory bowel diseases and irritable bowel syndrome in an increasing number of randomized controlled trials. Recently published data gives striking insights into the factors associated with FMT success paving the road for the use of precision medicine in gastrointestinal disorders.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research
DiscussionThis multicenter randomized controlled trial may provide high-quality evidence on the efficacy of theBifidobacterium quadruple viable tablet for IBS-D on both physical and mental dimensions in China. To fill the gap of previous probiotic intervention studies, in addition, this study will also present safety assessment which will be a significant emphasis.Trial registrationChiCTR1800017721. Registered on 10 August 2018.
Source: Trials - Category: Research Source Type: clinical trials
Conclusions: Supplementation of SAMe and L. plantarum HEAL9 in adults with subthreshold or mild-to-moderate symptoms of depression resulted in fast and clinically relevant effects after 2 weeks. The combination was safe and significantly improved symptoms of depression, anxiety, and cognitive and somatic components. The effect of this novel product is independent from the severity of the symptoms unlike traditional antidepressants available on the market that have minimal benefits for subthreshold or mild-to-moderate symptoms. Trial Registration: ClinicalTrials.gov identifier: NCT03932474. PMID: 32589828 [PubMed - ...
Source: The Primary Care Companion for CNS Disorders - Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
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