Irritable Bowel Symptoms Tied to Intestinal, Brain Abnormalities

FRIDAY, June 7, 2019 -- A greater number of intestinal and brain function abnormalities increases the burden of irritable bowel syndrome (IBS), according to a study recently published in Gastroenterology. Magnus Simr én, M.D., Ph.D., from the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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The FDA has authorized marketing of the first medical device for adolescents with abdominal pain associated with irritable bowel syndrome (IBS). The device, which is available by prescription only, is indicated for patients aged 11 through 18 years.
Source: JAMA - Category: General Medicine Source Type: research
There is controversy about whether psychological factors (anxiety and depression) increase seeking of healthcare by patients with irritable bowel syndrome (IBS). We investigated whether psychological factors increase healthcare seeking by patients with IBS and the effects of extra-GI symptoms.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Section Source Type: research
AbstractTo investigate long-term health sequelae of cryptosporidiosis, with especial reference to post-infectious irritable bowel syndrome (PI-IBS). A prospective cohort study was carried out. All patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, UK, aged between 6  months and 45 years of age, over a 2-year period were contacted. Five hundred and five patients agreed to participate and were asked to complete questionnaires (paper or online) at baseline, 3 and 12 months after diagnosis. The presence/absence of IBS was established using the Rome III criteria for different age groups. Tw...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
We report the chemical synthesis of this physiologically important oxysterol beginning with cholesterol. The key feature of this synthesis involves a regioselective C3-allylic oxidation of a 3-desoxy-Δ4-7α-formate steroid precursor to form 7α-formyloxy-cholest-4-en-3-one, which was saponified to yield 7α-hydroxy-cholest-4-en-3-one.Graphical abstract
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Publication date: October 2019Source: Biomedicine &Pharmacotherapy, Volume 118Author(s): Qiuke Hou, Shuilian Zhu, Changrong Zhang, Yongquan Huang, Yajuan Guo, Peiwu Li, Xinlin Chen, Yi Wen, Quanbin Han, Fengbin LiuAbstractTo investigate effects of berberine exerts on A20 expression and regulation of intestinal epithelial tight junctions via the TNF-α-NF-κB-MLCK pathway in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D).C57BL/6 wild type (WT) and A20 IEC-KO mice (48 each) were randomly divided into normal control (NC), model control (MC), rifaximin and berberine groups (12 mice per group). An experimen...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Conditions:   Non-celiac Gluten Sensitivity;   Irritable Bowel Syndrome Interventions:   Dietary Supplement: diet containing gluten;   Dietary Supplement: Placebo Sponsor:   University of Bari Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Students (female especially) suffer from ED and IBS, with a significant risk of co-existing ED-IBS. ED and IBS are related to multiple mental health symptoms, which could lead to negative academic consequences. Screening, using simple and quick tests as SCOFF questionnaire and ROME IV criteria (update of ROME III in 2016), is essential in this population of university students. PMID: 31288955 [PubMed - as supplied by publisher]
Source: Revue d Epidemiologie et de Sante Publique - Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research
Conditions:   Non-celiac Gluten Sensitivity;   Irritable Bowel Syndrome Interventions:   Dietary Supplement: diet containing gluten;   Dietary Supplement: Placebo Sponsor:   University of Bari Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
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