Congenital Refractory Glaucoma: A New Ophthalmic Association of Kabuki Syndrome and its Management With Glaucoma Drainage Devices

Discussion: This case confirms congenital glaucoma as a rare association of KS, and highlights the potential high-risk nature of such cases. In our opinion, the presence of high levels of inflammation perioperatively and postoperatively is an indication for primary glaucoma drainage device surgery given the high risk of bleb scarring resulting in recurrent surgical revisions. In view of these observations, we also advocate the use of intensive postoperative anti-inflammatory therapy.
Source: Journal of Glaucoma - Category: Opthalmology Tags: Online Articles: Case Report/Small Case Series Source Type: research

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Publication date: Available online 4 September 2019Source: Progress in Retinal and Eye ResearchAuthor(s): M. Elizabeth Fini, Shinwu Jeong, Haiyan Gong, Rafael Martinez-Carrasco, Nora M.V. Laver, Minako Hijikata, Naoto Keicho, Pablo ArgüesoAbstractThe mucosal glycocalyx of the ocular surface constitutes the point of interaction between the tear film and the apical epithelial cells. Membrane-associated mucins (MAMs) are the defining molecules of the glycocalyx in all mucosal epithelia. Long recognized for their biophysical properties of hydration, lubrication, anti-adhesion and repulsion, MAMs maintain the wet ocular su...
Source: Progress in Retinal and Eye Research - Category: Opthalmology Source Type: research
In this study we assessed the diagnostic usefulness of transorbital sonography in IIH with a special focus on color Doppler imaging of the central retinal artery. IIH patients presented papilledema and enlarged ONSD. ONSD accurately predicted an increased intracranial pressure in IIH (cut-off: 5.8 mm, 81% sensitivity, 80% specificity). 24 h following therapeutic lumbar puncture ONSD diminished significantly, whereas papilledema was not changed. PSV (peak systolic velocity) and Vmean (mean flow velocity) of the central retinal artery were increased in IIH patients compared to controls. PSV accurately predicted an increa...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Ascorbic acid and retinol palmitate modulatory effect on omeprazole-induced oxidative damage, and the cytogenetic changes in S. cerevisiae and S180 cells. Chem Biol Interact. 2019 Sep 25;311:108776 Authors: Paz MFCJ, Braga AL, de Meneses APM, de Carvalho RM, de Aguiar RPS, Cronemberger LAC, da Silva MBS, de Lima RMT, de Alencar MVOB, Duarte JL, Islam MT, Marcelo de Castro E Sousa J, Mubarak MS, Melo-Cavalcante AAC Abstract Omeprazole (OM), a prototype proton pump inhibitor, oxidizes thiol groups and induces DNA damage. The aim of this study was to evaluate the oxidative effects of omeprazole and its...
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
Seven years ago, Jason Esterhuizen was in a horrific car crash that destroyed his eyes, plunging him into total darkness. Today, he ’s regained visual perception and more independence, thanks to an experimental device implanted in his brain by researchers at UCLA Health.“Now I can do things that I couldn’t do before,” said Esterhuizen, 30, who moved from his native South Africa to participate in the clinical trial at UCLA. “I can sort the laundry, find my way in lighted hallways without using a cane and cross the street more safely. It’s making my life mu ch easier.”The device...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Condition:   Non-traumatic Subarachnoid Haemorrhage Intervention:   Diagnostic Test: retinal vascular analysis Sponsor:   RWTH Aachen University Recruiting
Source: - Category: Research Source Type: clinical trials
Conclusion: The use of maltodextrin and xanthan gum showed to be viable in the spray dryer and lyophilization drying processes.
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research
Authors: Sadick N, Edison BL, John G, Bohnert KL, Green B Abstract Background: Facial chemical peels are highly sought after by patients with photodamage, acne, and melasma. An advanced, physician-strength superficial peel, containing 3% retinol with other firming and volumizing ingredients was developed to exfoliate, improve the appearance of fine lines and wrinkles, and plump and firm skin, while promoting a bright, even complexion. Objective: A clinical study was conducted to evaluate the tolerability, safety, and efficacy of the 3% retinol peel with a supportive homecare regimen across a range of peel candidat...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
WEDNESDAY, Sept. 18, 2019 -- Butternut squash, Brussels sprouts and apples are all amazing fall superfoods and the perfect reason to get cooking. Cheap and versatile, butternut squash is loaded with fiber and vitamin A. For an easy butternut squash...
Source: - Daily MedNews - Category: General Medicine Source Type: news
This article reviews complications and adverse events of plaque brachytherapy, including scleral necrosis, strabismus, cataract, glaucoma, and retinopathies as well as management of these conditions. For practicing oncologists and ophthalmologists, these complications are important to understand, identify, and treat. Additionally, an understanding of common complications of brachytherapy should influence the decision of pursuing it as a treatment option. PMID: 31523242 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Eye, Published online: 18 September 2019; doi:10.1038/s41433-019-0564-2Circumpapillary and macular vessel density assessment by optical coherence tomography angiography in eyes with temporal hemianopia from chiasmal compression. Correlation with retinal neural and visual field loss
Source: Eye - Category: Opthalmology Authors: Source Type: research
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