A multi-component, family-focused and literacy-sensitive intervention to improve medication adherence in patients with heart failure –A randomized controlled trial

Medication nonadherence is prevalent and links to serious outcomes (e.g., rehospitalization/death) in heart failure (HF) patients; therefore, an urgent need exists for an intervention to improve and sustain adherence after intervention completion.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research

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ConclusionNYHA class IV was a significant predictor of all-cause death in both sexes with preserved EF, while NYHA class IV was a significant predictor of all-cause death in women, but not in men, in reduced EF patients.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 21 August 2019Source: Journal of Geriatric OncologyAuthor(s): Guillaume Beinse, Delphine Reitter, Lauriane Segaux, Muriel Carvahlo-Verlinde, Benoit Rousseau, Christophe Tournigand, Tristan Cudennec, Marie Laurent, Pascaline Boudou-Rouquette, Elena Paillaud, Florence Canouï-Poitrine, Philippe Caillet, for the ELCAPA Study GroupAbstractBackgroundBecause of comorbidities and polypharmacy, older patients with cancer have a greater risk of iatrogenic events. We aimed to characterize potential drug-drug interactions (PDIs) and the risk of unplanned hospitalization in older patients with ca...
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Authors: Róin T, Á Lakjuni K, Kyhl K, Thomsen J, Veyhe AS, Róin Á, Jan R, Marin S Abstract Objectives: Longer life expectancies imply increased prevalence of heart failure. Blittle is known about the maintenance of disease specific knowledge following patient education. Our aim was to investigate if self-care and heart failure knowledge persists at 9 month follow up among patients with heart failure after an outpatient programme in the Faroe Islands. Methods: A prospective cohort study with patients recently diagnosed with heart failure were recruited and evaluated by questionnaire ...
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research
ConclusionsThe role of mitral valve surgery and transcatheter mitral valve therapy continues to evolve.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsAmong individuals with CKD, single measurements of cFGF-23 improve prediction of risks for all-cause mortality and HF admission but not CV mortality, ESRD, or atherosclerotic events. Future studies should evaluate the predictive utility of repeated cFGF-23 testing.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
The risk of sudden cardiac death (SCD) appears to be higher among heart failure patients who also have HIV infection, according to new findings.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Cardiology News Source Type: news
The trial failed to hit the primary endpoints of cardiovascular death or worsening heart failure, but the serelaxin story may not be dead, according to the trial's PI.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news
Contributors : Paolo Kunderfranco ; Marinos Kallikourdis ; Gianluigi CondorelliSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSingle-cell RNA sequencing is revolutionizing the mapping of tissues in physiology and pathology. Whilst immune responses are emerging as key mediators of heart failure, no thorough immune mapping of the ailing heart has been performed so far. Here we examined, at single-cell level, the cardiac immune composition after transverse aortic constriction, the standard murine model of non-ischemic heart failure. We identified the presence of most major immune cell s...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Pulmonary arterial hypertension (PAH) is a progressive disease mainly characterised by a widespread obstruction of distal pulmonary arteries [1]. Untreated, this disease rapidly leads to right heart failure, then to death [2]. Heritable PAH (hPAH) represents about 30% of PAH cases, and this category includes familial forms with or without identified mutations, and sporadic forms carrying a mutation. The first genetic abnormalities discovered in hPAH were bone morphogenetic protein receptor-2 (BMPR2) mutations. Loss of function of this receptor results in proliferation of vascular smooth muscle cells and selection of endoth...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Research letters Source Type: research
AbstractRecent large clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists, with the aim of verifying cardiovascular safety, have revealed that these medications have a preventative advantage on adverse cardiovascular outcomes, including worsening of heart failure and deterioration of nephropathy, in patients with type 2 diabetes (T2D). These observed benefits do not seem to correlate with the glucose-lowering effect, and the underlying mechanism is being intensively investigated. Given the results from recent studies, the American Diabetes Association (A...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
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