Gene expression profiling and identification of hub genes in Nellore cattle with different marbling score levels.

The objective of this study was to use RNA-Seq to identify differentially expressed genes (DEGs) in muscle tissue (longissimus thoracis) of Nellore cattle divergently ranked on marbling, in order to increase our understanding of genes involved in the expression of this trait. The results revealed 49 DEGs and three hub genes (CISH, UFM1, TSHZ1), all of them involved in insulin and diabetes mellitus metabolism. These results indicating key genes and pathways, which may help to develop strategies designed to select animals with greater marbling. PMID: 31170441 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31170441?dopt=Abstract

Source: Genomics - June 2, 2019 Category: Genetics & Stem Cells Authors: Fonseca LFS, Dos Santos Silva DB, Gimenez DFJ, Baldi F, Ferro JA, Chardulo LAL, de Albuquerque LG Tags: Genomics Source Type: research