Lifespan trajectory of affect in Cornelia de Lange syndrome: towards a neurobiological hypothesis

ConclusionsLow affect in specific genetic syndromes may be associated with differing lifespan trajectories and behavioural profiles. Specifically, individuals with CdLS appear at risk for experiencing declines in levels of interest and pleasure whereas individuals with FXS show no significant change in the level of affect with age.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research