Mechanism and Risk Factors for Death In Adults with Tetralogy of Fallot

One of the goals of lifelong care in adults with tetralogy of Fallot (TOF) is early identification and treatment of patients at high risk for adverse events. Clinical risk stratification tools are critical for achieving this goal. We reviewed the MACHD (Mayo Adult Congenital Heart Disease) database and identified 465 TOF patients (age 37 ±14 years, males 223 [48%]) seen at Mayo Clinic Rochester between 1990 and 2017. The aim was to determine the risk factors for death and/or heart transplant through a comprehensive analysis of 8 groups of variables (demographics, comorbidities, medications, heart rhythm, echocardiography, cardiac m agnetic resonance imaging, cardiac catheterization, and cardiopulmonary exercise test data) using univariable and multivariable Cox proportional hazard models.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research