Cytokine expression in temporal arteries: comparative analysis between patients with biopsy-positive giant cell arteritis, biopsy-negative giant cell arteritis and biopsy-negative without arteritis.

CONCLUSIONS: IL-6, COX-2 and OPN are significantly more expressed in the presence of a positive TAB compared to a negative TAB. TNF-α is significantly more expressed in GCA patients compared to non-GCA patients. Thus, TNF-α expression may suggest a diagnosis of GCA despite a negative TAB. Further larger studies are needed to confirm these findings. PMID: 31162032 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31162032?dopt=Abstract

Source: Clinical and Experimental Rheumatology - June 6, 2019 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

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