This Month in The Journal

Even within tissue-specific databases, there is still a large amount of heterogeneity, possibly due to the various cell types that compose a specific tissue. It is possible that tissue-specific associations could be further refined if these associations could be explored at the level of cell type. However, rather than waiting until cell atlases become more readily available, one might be able to use in silico approaches to deconvolute the cell type composition of a tissue sample and then use this information to reassess associations with a given trait or disease.
Source: The American Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Tags: Editors ’ Corner Source Type: research