Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1 β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt.

CONCLUSIONS This work revealed that loganin treatment attenuated IL-1ß-treated apoptosis and ECM catabolism in rat chondrocytes via regulation of the PI3K/Akt signaling, revealing that loganin is a potentially useful treatment for OA. PMID: 31162482 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31162482?dopt=Abstract

Source: Medical Science Monitor - June 6, 2019 Category: Research Tags: Med Sci Monit Source Type: research