Cardiovascular and renal outcomes of incretin-based therapies: A review of recent clinical trials.

Cardiovascular and renal outcomes of incretin-based therapies: A review of recent clinical trials.
Curr Cardiol Rev. 2019 Jun 03;:
Authors: Kyriakos G, Quiles-Sanchez LV, Garmpi A, Farmaki P, Kyre K, Savvanis S, Memi E
Abstract
BACKGROUND: To report the cardiovascular and renal effects of incretin-based therapies.
METHOD: The studies of clinical trials on incretin-based therapy published in medical journals from years 2010 to 2017 were comprehensively searched using MEDLINE and EMBASE with no language restriction. The studies were reviewed and the cardiovascular and renal risks reported were recorded.
RESULTS: Incretin-based therapeutics represent novel and promising anti-diabetes drugs, the direct cardiovascular actions of which may translate into demonstrable clinical benefits on cardiovascular outcomes. Furthermore incretin-based therapies do not adversely affect renal function.
PMID: 31161994 [PubMed - as supplied by publisher]

Source: Current Cardiology Reviews - June 5, 2019 Category: Cardiology Tags: Curr Cardiol Rev Source Type: research