Efficacy and Safety of Real Life Usage of MiniMed 670G Automode in Children with Type 1 Diabetes Less than 7 Years Old

Diabetes Technology&Therapeutics, Ahead of Print.
Source: Diabetes Technology - Category: Endocrinology Authors: Source Type: research

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In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Publication date: Available online 18 October 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Eleanor P Thong, Ethel Codner, Joop S E Laven, Helena TeedeSummaryReproductive dysfunction is a common but little studied complication of diabetes. The spectrum of reproductive health problems in diabetes is broad, and encompasses delayed puberty and menarche, menstrual cycle abnormalities, subfertility, adverse pregnancy outcomes, and potentially early menopause. Depending on the age at diagnosis of diabetes, reproductive problems can manifest early on in puberty, emerge later when fertility is desired, or occur duri...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
In this study, we generated a type 1 diabetes (T1D) mouse model by STZ injection to study the effects of T1D on zona pellucida and genomic DNA methylation of oocytes and granulosa cells. T1D mice showed fewer ovulated eggs, reduced ovarian reserve, disrupted estrus cycle, and significantly ruptured zona pellucida in 2-cell in vivo embryos compared to controls. Notably, diabetic oocytes displayed thinner zona pellucida and treatment of oocytes with high concentration glucose reduced the zona pellucida thickness. Differential methylation genes in oocytes and granulosa cells were analyzed by methylation sequencing. These gene...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Publication date: May 2020Source: Value in Health Regional Issues, Volume 21Author(s): Xiaomeng Yue, Jiuhong Wu, Zhen Ruan, Michael L. Wolden, Lanting Li, Yong LinAbstractBackgroundHypoglycemia is a common acute complication in patients with diabetes and markedly impacts on medical resource use.ObjectivesTo make an initial assessment of the incidence of hypoglycemia and the associated utilization of medical resources and medical costs in insulin-treated patients with diabetes using medical records from 4 tertiary hospitals in China.MethodsA retrospective cohort study was conducted using electronic medical records from 4 te...
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
Authors: Hylmarova S, Stechova K, Pavlinkova G, Peknicova J, Macek M, Kvapil M Abstract Little is known about type 1 diabetes mellitus (T1DM) impact on the male sexual and reproductive functions. We aim to evaluate the influence of T1DM on male sexual function, quality of sexual life, and sex hormone levels. A total of 57 male patients aged 18 to 50 years (mean = 33) with T1DM (duration mean = 15 years) had a medical examination and completed a set of questionnaires - International Index of Erectile Function-5 (IIEF-5), Beck Depression Inventory (BDI) and Sexual quality of life questionnaire male (SQoL-M). The prev...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Publication date: December 2019Source: Biomedicine &Pharmacotherapy, Volume 120Author(s): Eman A. Abd El-Ghffar, Nesrine M. Hegazi, Hamada H. Saad, Mohamed M. Soliman, Mohamed A. El-Raey, Safia M. Shehata, Alaa Barakat, Aziz Yasri, Mansour SobehAbstractThe phenolic profile of the leaves of Beta vulgaris subspecies vulgaris variety rubra was investigated by high-performance liquid chromatography (HPLC) coupled to electrospray ionization high resolution mass spectrometric (ESI-HRMS-MS) detection. Mass spectrometry-based molecular networking was employed to dereplicate the known compounds. Twelve known compounds, seven of...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Condition:   Insulin-Dependent Diabetes Mellitus 1 Interventions:   Other: High GI calculated by CC (CHGI);   Other: Low GI calculated by CC (CLGI);   Other: High GI calculated by FII (FHGI);   Other: Low GI calculated by FII (FLGI) Sponsor:   TC Erciyes University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9NJ02460C, PaperSamuel Trevi ño, Enrique Gonzalez-Vergara Diabetes mellitus is a pandemic expected to spread from 422 million patients in 2014 to 592 million patients in 2035. Type 1 diabetes mellitus (T1D) is characterized by both autoimmune... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Sensors, Vol. 19, Pages 4538: On the Possibility of Predicting Glycaemia ‘On the Fly’ with Constrained IoT Devices in Type 1 Diabetes Mellitus Patients. Sensors doi: 10.3390/s19204538 Authors: Rodríguez-Rodríguez Rodríguez Chatzigiannakis Zamora Izquierdo Type 1 Diabetes Mellitus (DM1) patients are used to checking their blood glucose levels several times per day through finger sticks and, by subjectively handling this information, to try to predict their future glycaemia in order to choose a proper strategy to keep their glucose levels under control, in terms of insulin d...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
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