Why colchicine should continue to be the first line therapy for acute and recurrent pericarditis

Publication date: Available online 4 June 2019Source: Revista Española de Cardiología (English Edition)Author(s): Massimo Imazio
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research

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Authors: Andreis A, Imazio M, De Ferrari GM Abstract Introduction: Acute pericarditis is frequently complicated with recurrences, which represent a diagnostic and therapeutic challenge for the physician, a bothersome trouble for patients. An incorrect treatment of pericarditis may cause further recurrence of symptoms, while an incorrect diagnosis may cause either a prolonged symptoms course with a possible risk of chronic constriction, or useless and potentially harmful treatments.Areas covered: This review will focus on the most useful and recent diagnostic tools for recurrent pericarditis. Medline/Pubmed Library ...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
Publication date: Available online 9 November 2019Source: Microbial PathogenesisAuthor(s): Gilneia da Rosa, Davi Fernando Alba, Anielen D. Silva, Anderson Gris, Ricardo E. Mendes, Vitor B. Mostardeiro, Thalison F. Lopes, Maria Rosa Chitolina, Lenita M. Stefani, Marcos T. Lopes, Marcel Manente Boiago, Aleksandro S. da SilvaAbstractThe aim of this study was to determine whether oxidative stress occurs in Escherichia coli-infected broiler breeder chicks, as well as the impact of this infection on bird growth. Twenty birds, 25-day-old female birds were divided into two groups (n = 10 per group): an intraperitoneally-infect...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Authors: Nguta JM Abstract Nitrate toxicosis associated with consumption of cabbages (Brassica oleracea var. capitata L.) (Brassicaceae) was diagnosed in a small herd comprising of ten goats in Matinyani ward, Kitui West sub-County of Kitui County in Kenya. The clinical signs were ataxia, ruminal tympany, bluish-brown mucous membranes, rapid and difficult breathing, incoordination, head pressing, aggressive movements, jugular distension, increased heart rates, tremors, and coma. Six goats died of intoxication. Dark brown/chocolate-colored and poorly clotted blood was the prominent necropsy finding. There was limite...
Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
ConclusionsDescending necrotizing mediastinitis due to blunt neck trauma is a rare occurrence, but can lead to late sequential bilateral empyema even after 18 days. With early diagnosis, aggressive drainage and antibiotic therapy, the patient life can be saved.The lesson we took from this case is that: 1- blunt neck trauma rarely leads to descending necrotizing mediastinitis and late sequential empyema (even after 18 days).2-If the patient does not recover from sepsis, despite optimal surgical management, contra lateral empyema or pericarditis should be considered.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
New research seeking to describe the characteristics of undefined, systemic autoinflammatory diseases may have identified distinct subgroups, including pericarditis and intellectual impairment...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Systemic Inflammatory Syndromes Familial Mediterranean fever Orphan Autoinflammatory Disorders Systemic inflammatory disease Source Type: research
Written by Meyers, edits by SmithA 50-ish year old man was working construction when he suddenly collapsed. Coworkers started CPR within 1 minute of collapse. EMS arrived within 10 minutes and continued CPR and ACLS, noting alternating asystole and sinus bradycardia during rhythm checks. He received various ACLS medications and arrived at the ED with a perfusing rhythm.Initial vitals included heart rate around 100 bpm and BP 174/96. Here is his initial ECG, very soon after ROSC:What do you think?Sinus tachycardia.  There is incomplete RBBB (QRS duration less than 120 ms).  There is diffuse STD, maximal in V4-V5 a...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Extragenital manifestations of Chlamydia trachomatis infection can be challenging to diagnose. A previously healthy 33-year-old man presented with pericarditis recurring despite anti-inflammatory therapy and progressing to cardiac tamponade. Pericardiocentesis yielded bloody-appearing fluid with increased neutrophils and negative standard cultures. The patient reported recent unprotected sexual exposure, and urine nucleic acid amplification test detected C. trachomatis. He had no urogenital, ocular, or joint symptoms. The result of an extensive workup for other causes of pericarditis was negative, including HLA-B27 testing...
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research
CONCLUSION: To our knowledge, this uncommon association is described for the first time. Few studies have analyzed the implications of HTLV-1 infection in thyroiditis and diabetes mellitus. We did not find any reports describing the association of pericarditis with HTLV-1 infection. Additional studies are necessary to understand the role of HTLV-1 in endocrine and cardiac disorders. PMID: 31654516 [PubMed - as supplied by publisher]
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Tags: Curr Diabetes Rev Source Type: research
The objective of this study was to evaluate if infection by Escherichia coli in juvenile breeder chicks alters the activity of enzymes involved in neurotransmission and cerebral immunomodulation, including acetylcholinesterase (AChE), nucleoside triphosphate diphosphohydrolase (NTPDase), 5′-nucleotidase (5′NT) and adenosine deaminase (ADA), as well as their effects on the pathogenesis of the disease. We divided 20 growing breeder chicks into two groups (n = 10 per group). One group was experimentally infected with 1 mL of culture medium containing 1 × 108 CFU of E. coli intraperitoneally. The ...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
After publication of the original article [1], we were notified that an author ’s name is not complete.
Source: BMC Cardiovascular Disorders - Category: Cardiology Authors: Tags: Correction Source Type: research
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