UK's MHRA Offers Split Recs on Paclitaxel-Coated Devices in PAD UK's MHRA Offers Split Recs on Paclitaxel-Coated Devices in PAD

The agency acted to limit the future use of the devices in routine clinical care of intermittent claudication but left open their use in critical limb ischemia.News Alerts
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Alert Source Type: news

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It might be questioned why the careful, but invasive, scientific study by Gratl et  al.1 should be published in this journal, because it has no immediate clinical application. The study shows that muscle mitochondrial function is depressed in the leg muscle of patients with isolated superficial femoral artery (SFA) lesions causing intermittent claudication (Fontaine stage IIb or III) disease, but that gastrocnemius mitochondrial function is normalised six weeks after successful revascularisation.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Invited Commentary Source Type: research
Axillary bilateral femoral bypass is often utilized as an alternative to in-line aortic reconstruction in patients with multiple medical comorbidities who would be unable to tolerate open abdominal surgery with an aortic clamp or patients with mycotic aneurysms or infected grafts. Idealized fluid mechanics suggest that there would be equal flow in an axillary bilateral femoral bypass when compared to in-line reconstruction. However, in a non-idealized state, friction results in kinetic energy loss and decreased volume flow to the lower extremities in the longer, smaller diameter graft.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
We present the case of an 8-year-old girl who developed acute decompensated cardiac, respiratory, and renal failures due to the occlusion of the descending aorta secondary to Takayasu arteritis (TA).
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
We report two young claudicants, treated with primary stenting with continuous 4 and 10-year symptomatic relief and arterial patency.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
Peripheral arterial disease (PAD) is a highly prevalent, yet underdiagnosed, condition [1]. Although frequently asymptomatic, it is a leading cause of leg pain, claudication, ulceration, gangrene, and even amputation. On the other hand, patients with type 2 diabetes (T2DM) are more likely to develop PAD than do the non-diabetic subjects. Furthermore, they are affected by more severe and extensive form of the disease that tends to involve more distal arteries, progress more quickly, and also it is more likely to lead to ischemic ulceration and amputation [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
a DAG PMID: 31612216 [PubMed - as supplied by publisher]
Source: Physical Therapy - Category: Physiotherapy Authors: Tags: Phys Ther Source Type: research
Conclusion: The patterns of physical activity of PAD patients are characterized by a large amount of time spent in sedentary behaviors and a low engagement in MVPA. Younger patients, regardless of the clinical and functional factors, were more likely to meet the current physical activity recommendations.Resumo Fundamento: Aumentos nos n íveis de atividade física diária são recomendados para pacientes com doença arterial periférica (DAP). No entanto, apesar dessa recomendação, pouco se sabe sobre os padrões de atividade física dos pacientes com DAP. Objet...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Conclusion: The patterns of physical activity of PAD patients are characterized by a large amount of time spent in sedentary behaviors and a low engagement in MVPA. Younger patients, regardless of the clinical and functional factors, were more likely to meet the current physical activity recommendations.Resumo Fundamento: Aumentos nos n íveis de atividade física diária são recomendados para pacientes com doença arterial periférica (DAP). No entanto, apesar dessa recomendação, pouco se sabe sobre os padrões de atividade física dos pacientes com DAP. Objet...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Abstract BACKGROUND: Endovascular treatment of occlusive disease of the superficial femoral artery (SFA) has evolved from plain old balloon angioplasty (POBA) through primary stenting strategy to drug eluting technology-based approach. The RAPID trial investigates the added value of drug coated balloons (DCB, Legflow) in a primary stenting strategy (Supera stent) for intermediate (5-15 cm) and long segment (>15 cm) SFA lesions. METHODS: In this multicenter, patient-blinded trial, 160 patients with intermittent claudication, ischemic rest pain, or tissue loss due to intermediate or long SFA lesions were ran...
Source: The Journal of Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: J Cardiovasc Surg (Torino) Source Type: research
Claudication is pain, cramping, or fatigue in the muscles that usually occurs during exercise and goes away with rest. Learn about why it happens, what it feels like, and treatments here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Blood / Hematology Source Type: news
More News: Cardiology | Heart | Intermittent Claudication