A biased coin up-and-down sequential allocation trial to determine the optimum programmed intermittent epidural bolus time interval between 5 mL boluses of bupivacaine 0.125% with fentanyl 2 µg·mL-1.

CONCLUSION: The EI90 between 5 mL boluses of bupivacaine 0.125% with fentanyl 2 µg·mL-1 during the first stage of labour is approximately 35 min. TRIAL REGISTRATION: www.clinicaltrials.gov (NCT #02758405); registered 2 May, 2016. PMID: 31152372 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31152372?dopt=Abstract

Source: Canadian Journal of Anaesthesia - May 30, 2019 Category: Anesthesiology Authors: Bittencourt R, Arzola C, Zakus P, Downey K, Ye XY, Carvalho JCA Tags: Can J Anaesth Source Type: research