New study links childhood abuse with hot flash frequency
(The North American Menopause Society (NAMS)) Numerous adverse health outcomes have been linked to childhood maltreatment, including mental illness, cardiovascular disease, and premature mortality. A new study suggests that childhood abuse (which was found to have occurred in 44% of the sample population) may also cause more hot flashes, especially during sleep. Results are published online today in Menopause, the journal of The North American Menopause Society.
Conditions: Sleep Apnea; Post Menopausal; Oxidative Stress Intervention: Drug: Duavive (0.45 estrogens mg and 20 mg bazedoxifene) Sponsors: Laval University; V Joseph; C Minville; C Rheaume Not yet recruiting
Cognitive behavioural therapy (CBT) can effectively reduce menopause symptoms including hot flushes, depression and sleep problems, according to a study published inMenopause.Medical News Today
Conclusion: TX-001HR significantly improved MOS-Sleep parameters from baseline to week 12, which was sustained for up to 12 months, and was associated with a very low incidence of somnolence.
Objective: To characterize the impact of TX-001HR on the relationship between vasomotor symptom (VMS) improvement and quality of life and sleep. Methods: REPLENISH (NCT01942668) was a phase 3, randomized, double-blind, placebo-controlled, multicenter trial, which evaluated four daily doses of 17β-estradiol and progesterone (E2/P4) combined in a single, oral, softgel capsule in postmenopausal women (40-65 years) with a uterus and moderate to severe VMS (≥7/day or ≥50/week). In post hoc analyses, growth models were used to examine relationships between linear changes in VMS frequency and severity over 12 week...
DiscussionIf the results confirm that acupuncture is effective and safe for the treatment on insomnia in menopausal women, this positive outcome could provide evidence for clinical application.Trial registrationChinese Clinical Trial Registry,ChiCTR1800018645. Registered on 10 January 2018.
Depressive symptoms are common yet potentially serious in mid-aged women, particularly during the menopausal transition, when hormonal fluctuations occur. Different drug treatments have been recommended; although many women do not follow them. There are conflicting results from observational studies concerning the effect of exercise on depressive/anxiety symptoms, sleep and perceived stress in postmenopausal women. Meta-analyses of randomized clinical trials (RCTs) provide a global approach to obtain recommendations.
Introduction: It is known that hypoxia during obstructive sleep apnea syndrome (OSAS) is a stress factor which may change free radical homeostasis, manifested in reactive oxygen products deficiency and activation of lipid peroxidation. The data about oxidative stress and OSAS association are ambiguous. The aim of this research is to assess lipid peroxidation (LPO) and antioxidant defense system (AOD) parameters in menopausal women with different severity of OSAS.
Introduction: It is known that menopausal women have sleep disorders. Currently it has been shown that both the prevalence and structure of sleep disorders and its characteristics are dependent on ethnicity. The aim of this research is to evaluate the features of insomnia in Caucasian and Asian peri- and postmenopausal women.
Introduction: Glutathione system is the one of the important components of the antioxidant defense system which protects against oxidative stress. Its activity is determined by the polymorphic variants of the corresponding genes. Along with this, it is possible, that main consequences of sleep loss may be oxidative stress. The aim of this research is to assess lipid peroxidation and antioxidant protection system parameters in Caucasian menopausal women with insomnia depending on the glutathione S-transferase M1 genotype.
Introduction: According to the current data, most menopausal women have reduced quality of life and one of the main criteria of it is sleep disturbances. It is highly possible, that main consequences of sleep loss may be oxidative stress. Glutathione system is the one of the important components of the antioxidant defense system, which includes glutathione and enzymes. It has been shown that the activity of these enzymes is determined by the polymorphic variants of the corresponding genes. The aim of this research is to carry out a comparative analysis of the frequency distribution of Glutathione S-transferase T1 (GSTT1) a...