MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine [Biochemistry]

The cell envelope of Mycobacterium tuberculosis is notable for the abundance of mycolic acids (MAs), essential to mycobacterial viability, and of other species-specific lipids. The mycobacterial cell envelope is extremely hydrophobic, which contributes to virulence and antibiotic resistance. However, exactly how fatty acids and lipidic elements are transported across the...

Source: Proceedings of the National Academy of Sciences - June 3, 2019 Category: Science Authors: Chih-Chia Su, Philip A. Klenotic, Jani Reddy Bolla, Georgiana E. Purdy, Carol V. Robinson, Edward W. Yu Tags: Biological Sciences Source Type: research