Su1370 INITIAL EXPERIENCE OF NITROUS OXIDE CRYOBALLOON ABLATION FOR ERADICATION OF NONPOLYPOID SPORADIC AND FAMILIAL ADENOMATOUS POLYPOSIS (FAP) DUODENAL ADENOMAS

Duodenal adenomas (DA) can progress to high grade dysplasia (HGD) in 21% of cases. When> 2 cm in size, more than half can harbor invasive cancer. Familial adenomatous polyposis (FAP) patients are at high risk for duodenal cancer arising from DA. Endoscopic mucosal resection (EMR) is generally the preferred treatment but is associated with an overall adverse event rate of 26%, primarily from bleeding, particularly those>3 cm in size (incidence 33-58%). Cryotherapy using the focal cryoballoon ablation system (C2 Cryoballoon ®, Pentax) can safely and effectively eradicate esophageal intestinal metaplasia with dysplasia.

Source: Gastrointestinal Endoscopy - May 31, 2019 Category: Gastroenterology Authors: Olaya I. Brewer Gutierrez, David L. Diehl, Richard Kwon, Nirav Thosani, Mohamad Dbouk, Harshit S. Khara, Tossapol Kerdsirichairat, Marcia I. Canto Tags: Sunday abstract Source Type: research