Mo1693 STUDY OF THE PROTEOMIC PROFILE IN PATIENTS WITH CROHN'S DISEASE, ITS CORRELATION WITH DIAGNOSIS AND DISEASE ACTIVITY

Inflammatory bowel diseases (IBD) include two major forms of chronic intestinal disorders: Crohn ’s disease (CD) and ulcerative colitis (UC). CD can be associated with intestinal granulomas, strictures, fistulas, and transmural inflammation. A single gold standard for the diagnosis of CD is not available. The diagnosis is confirmed by clinical evaluation and a combination of endoscopic, histo logical, radiological, and/or biochemical investigations. Serum protein profiling of CD was investigated in order to improve the comprehension of the pathologic mechanisms and to support the difficult diagnostic procedures currently available.The aim of the work is to identify plasma proteomic profi les of CD cases and correlating this profile with the other diagnostic markers and activity of the disease.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Monday abstract Source Type: research