The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway

Previous study demonstrated that extracellular ATP could promote cell migration and invasion in multiple human cancers. Till now, the pro-invasive mechanisms of ATP and P2RX6, a preferred receptor for ATP, are...

Source: Journal of Experimental and Clinical Cancer Research - June 3, 2019 Category: Cancer & Oncology Authors: Dongkui Gong, Jin Zhang, Yonghui Chen, Yunfei Xu, Junjie Ma, Guanghui Hu, Yiran Huang, Junhua Zheng, Wei Zhai and Wei Xue Tags: Research Source Type: research