A novel genotype of Leptospira interrogans recovered from leptospirosis outbreak in southern Thailand.

A novel genotype of Leptospira interrogans recovered from leptospirosis outbreak in southern Thailand. Jpn J Infect Dis. 2019 May 31;: Authors: Thongdee M, Chaiwattanarungruengpaisan S, Lekcharoen P, Yimchoho N, Buathong R, Wiriyarat W Abstract   We performed Leptospira culture of 76 clinical samples collected from animals and 6 soil samples for the investigation of a leptospirosis outbreak in southern Thailand, 2017. Recovery of leptospires was found in a kidney sample of a fatal canine leptospirosis case and all of the soil samples. 16S rRNA sequence analysis demonstrated that the clinical isolate was closely related to the pathogenic L. interrogans while the soil isolates were related to different species including the pathogenic L. ellisii, the intermediate L. wolffii and the non-pathogenic L. yanagawae. Multilocus sequence typing (MLST) identified a novel sequence type (ST) of the isolate of L. interrogans in ST263, suggesting the causative agent of canine leptospirosis in the southern Thailand outbreak has a unique genetic profile. PMID: 31155602 [PubMed - as supplied by publisher]
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research

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