ECG Challenge: Beating at a Fast Clip ECG Challenge: Beating at a Fast Clip

Whether it's related to his COPD, inhalers, neither, or both, this patient's ECG reveals why his pulse is so fast.Medscape Cardiology
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Cardiology Clinical Case Source Type: news

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The inflammatory responses in chronic airway diseases leading to emphysema are not fully defined. We hypothesised that lung eosinophilia contributes to airspace enlargement in a mouse model and to emphysema in patients with chronic obstructive pulmonary disease (COPD). A transgenic mouse model of chronic type 2 pulmonary inflammation (I5/hE2) was used to examine eosinophil-dependent mechanisms leading to airspace enlargement. Human sputum samples were collected for translational studies examining eosinophilia and matrix metalloprotease (MMP)-12 levels in patients with chronic airways disease. Airspace enlargement was ident...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: COPD and smoking, Lung biology and experimental studies, Asthma and allergy Original Articles: Airways disease and basic science Source Type: research
Might the risk of acute COPD exacerbations differ between biomass smoke and tobacco smoke exposure? In what ways?BMC Pulmonary Medicine
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news
AbstractSeveral factors have been associated with the development of asthma and asthma-related morbidity and mortality. Exposures in the environment such as allergens and air pollutants have traditionally been linked to the risk of asthma and asthma outcomes. More recent literature has identified chronic psychosocial stress as an additional environmental exposure to consider in relation to asthma. Adverse childhood events (ACEs) and chronic and toxic stress have been associated with chronic diseases such as cardiovascular disease, cancer, and chronic obstructive pulmonary disease. Chronic stress has also been shown to resu...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
Publication date: May–June 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 5Author(s): Richard H. Stanford, Carlyne Averell, Emily D. Parker, Cori Blauer-Peterson, Tyler K. Reinsch, Ami R. BuikemaBackgroundAlthough efficacy and safety of fluticasone furoate/vilanterol (FF/VI) and budesonide/formoterol (BUD/F) have been demonstrated in clinical studies, real-world comparisons of utilization have not been performed.ObjectiveTo compare similar patients with asthma initiating FF/VI or BUD/F on measures of adherence, persistence, and the asthma medication ratio (AMR).MethodsThis wa...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: May–June 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 5Author(s):
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: May–June 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 5Author(s): Ahmed Yousuf, Wadah Ibrahim, Neil J. Greening, Christopher E. BrightlingChronic obstructive pulmonary disease (COPD) is a significant cause of morbidity and mortality worldwide. In contrast to other chronic diseases, COPD is increasing in prevalence and is projected to be the third leading cause of death and disability worldwide by 2030. Recent advances in understanding the underlying pathophysiology of COPD has led to the development of novel targeted therapies (biologics and small molecule...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Nitrosative stress and a decrease of reactive persulfides and polysulfides, which are potent antioxidants, may contribute to the redox imbalance in the airways of patients with ACO and they may be associated with the pathogenesis.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Asthma –chronic obstructive pulmonary disease overlap (ACO) has frequent exacerbations and a poor quality of life and prognosis compared with those of chronic obstructive pulmonary disease alone. However, the pathogenesis of ACO has not been fully elucidated yet.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
An extended course of low-dose azithromycin may significantly reduce treatment failure in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (COPD), new data suggest.Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news
Publication date: Available online 26 April 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Adam Barczyk, Marta Maskey-Warzęchowska, Katarzyna Górska, Marek Barczyk, Krzysztof Kuziemski, Paweł Śliwiński, Halina Batura-Gabryel, Robert Mróz, Aleksander Kania, Andrzej Obojski, Maciej Tażbirek, Natalia Celejewska-Wójcik, Katarzyna Guziejko, Beata Brajer-Luftmann, Damian Korzybski, Iwona Damps-Kostańska, Rafał KrenkeABSTRACTBackgroundThe concordance between asthma-chronic obstructive pulmonary disease overlap (ACO) defined according to GINA/GOLD and other diagnostic ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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