The Influence of MR Contrast for PET Qualification in Pituitary Tumor with Simultaneous Integrated PET/MR

Conclusions: The feasibility of application of the GBCA on integrated simultaneous PET/MR was notarized and validated on account that the uptake ratio before and after the GBCA injection has not significant changes (P>0.05). Table.1. Average SUV difference between two periods and p value to show the statistical difference significance.cortex regionp valueDif. (%)Prefrontal Lateral R0.8021.36Prefrontal Lateral L0.7081.48Prefrontal Medial R0.8091.03Prefrontal Medial L0.7141.20Sensorimotor R0.8191.13Sensorimotor L0.7251.22Anterior Cingulate R0.7771.22Anterior Cingulate L0.6941.17Posterior Cingulate R0.7341.85Posterior Cingulate L0.5742.07Precuneus R0.8221.17Precuneus L0.7501.19Parietal Superior R0.9250.49Parietal Superior L0.8361.10Parietal Inferior R0.7311.73Parietal Inferior L0.6591.70Occipital Lateral R0.958-0.28Occipital Lateral L0.9690.15Primary Visual R0.876-0.91Primary Visual L0.813-1.36Temporal Lateral R0.7391.31Temporal Lateral L0.6381.61Temporal Mesial R0.5551.45Temporal Mesial L0.4151.94Cerebellum Whole00 Fig.1. MR and PET/MR images from a representative patient. Coronal T1 image (A) and enhanced T1 imgae(B), sagital T1 FS image (C) and enhanced T1 FS image (D), T2 propeller image (E), T2 FS Propeller image (F) are shown in the figure. Fused PET/MR (MAC-T1) and Fused enhanced PET/MR (MAC+-T1) are displayed in (G) and (H). The lesion is more clear in the enhanced MR image compared with traditional MR image. In other words, the lesion is not that clear in T1, T2,or e...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Tech Papers IV: Instrumentation & amp; Data Analysis Source Type: research

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Publication date: Available online 10 December 2019Source: Artificial Intelligence in MedicineAuthor(s): Sarah Ali Abdelaziz Ismael, Ammar Mohammed, Hesham HefnyAbstractCancer is the second leading cause of death after cardiovascular diseases. Out of all types of cancer, brain cancer has the lowest survival rate. Brain tumors can have different types depending on their shape, texture, and location. Proper diagnosis of the tumor type enables the doctor to make the correct treatment choice and help save the patient's life. There is a high need in the Artificial Intelligence field for a Computer Assisted Diagnosis (CAD) syste...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
__________ Just a heads-up about a great event later this week in Dublin, Ireland, for those working on virtual and augmented reality and healthcare innovation. When: Thu Dec 5, 2019 8:00 am — Fri Dec 6, 2019 5:00 pm. Where: Davenport Hotel Featured sessions include: Day 1 – Thursday, December 5th, 2019 9:00am‑9:30am Introductions, Welcome and Setting The Stage Robert Fine, Executive Director, International Virtual Reality and Healthcare Association (IVRHA) 9:30am-10:30am Keynote Presentation:  Virtual Reality and Healthcare: The Past, The Present and The Future Dr. Walter Gree...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Education & Lifelong Learning Health & Wellness Technology augmented reality Dublin healthcare healthcare innovation virtual-reality Source Type: blogs
Publication date: March 2020Source: Biomedical Signal Processing and Control, Volume 57Author(s): Navid Ghassemi, Afshin Shoeibi, Modjtaba RouhaniAbstractIn this paper, a new deep learning method for tumor classification in MR images is presented. A deep neural network is first pre-trained as a discriminator in a generative adversarial network (GAN) on different datasets of MR images to extract robust features and to learn the structure of MR images in its convolutional layers. Then the fully connected layers are replaced and the whole deep network is trained as a classifier to distinguish three tumor classes. The deep neu...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
CONCLUSION: A highly focused imaging protocol is important for the diagnosis of sellar lesions such as pituitary tumors. The current favored modality is contrast-enhanced MRI, preferably with dynamic contrast-enhanced T1-weighted sequences. Early detection of the lesions and identification of the precise anatomical location are of great importance for diagnosis and therapy. PMID: 31321467 [PubMed - as supplied by publisher]
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research
Derin Gebhardt, 37, from Roundup, Montana, was diagnosed in May 2017 with a pituitary tumor, which was causing a decrease in normal levels of sex hormones and behind his infertility.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionWe highlighted how pituitary apoplexy may mimic the clinical findings of an infectious meningoencephalitis, learning points on how clinical assessment can aid earlier diagnosis and the importance of considering this differential diagnosis, particularly with the associated morbidity and mortality.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
CONCLUSION: Neurological signs recorded in DPM-affected dogs include not only the typical forebrain signs but also gait disturbances and hyperesthesia. Neurological signs are positively associated with increased P:B ratio and MRI signs of brain compression. PMID: 31112462 [PubMed - as supplied by publisher]
Source: Veterinary Quarterly - Category: Veterinary Research Tags: Vet Q Source Type: research
Conclusions This review describes how leukocyte-heparanase can be a double-edged sword in tumor progression; it can enhance tumor immune surveillance and tumor cell clearance, but also promote tumor survival and growth. We also discuss the potential of using heparanase in leukocyte therapies against tumors, and the effects of heparanase inhibitors on tumor progression and immunity. We are just beginning to understand the influence of heparanase on a pro/anti-tumor immune response, and there are still many questions to answer. How do the pro/anti-tumorigenic effects of heparanase differ across different cancer types? Does...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Authors: Hirano M, Wada-Hiraike O, Miyamamoto Y, Yamada S, Fujii T, Osuga Y Abstract A 34-year-old woman presented our hospital with complaint of irregular menstruation and abnormal uterine bleeding lasting for a month. After her second parturition at the age of 27, her menstrual cycle had been regular, but it suddenly became irregular at the age of 30. Transvaginal ultrasound revealed the presence of ovarian mass, and the patient underwent diagnostic laparoscopic surgery. Bilateral ovaries temporally shrink after puncture but the size soon resumed. Gonadotropins were almost normal, but estradiol and PRL levels tur...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Conclusions: This study demonstrated a rapid improvement of many symptoms in the subacute post-operative period in pituitary tumor patients. Disturbed sleep was identified as the only symptom to worsen post-operatively, encouraging potential prospective interventions to improve sleep, and subsequently improve the QOL in pituitary tumor patients following surgical intervention. Introduction Pituitary tumors are relatively rare primary central nervous system (CNS) tumors in adults (1) but make up 10% of all neurosurgical interventions in the United States (2). They are often an incidental finding in autopsies and brain...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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