The Effect of Radioiodine Therapy on Ovarian Functionin Patients with Differentiated Thyroid Carcinoma

Conclusions: This study prospectively showed that the ovarian reserve declined rapidly at M2, with gradual recovery subsequently. The effect of therapy times on ovarian function and variation trend of other female hormones need further exploration. Key Words: Differentiated thyroid cancer, Anti-Müllerian hormone, Ovarian function
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Endocrinology (Clinical Therapy) Posters Source Type: research

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Conclusions: the factors associated with cervical adenocarcinoma were ≥ 40 years old, ≤ 3 years of schooling, black race, menopausal status, never had undergone cervical cancer screening and the presence of HPV.Resumo Objetivos: determinar a incid ência dos principais Papilomavirus Humano (HPV) de alto risco oncogênico (16, 18, 31 e 33) e os fatores associados ao adenocarcinoma do colo uterino. Métodos: realizado estudo de caso-controle com 324 mulheres (69 com adenocarcinoma e 260 controles saudáveis), de 2001 a 2014. Foram colhidas inf ormações sobre fatores de risco associad...
Source: Revista Brasileira de Saude Materno Infantil - Category: Midwifery Source Type: research
In this study, the effects of Leucaena on different female reproductive variables were analyzed in two different reproductive conditions: gonadally intact and ovariectomized (OVX) female rats. Leucaena (LEU) was administered to females in both experimental conditions for 30 consecutive days. The effects of the legume extract were compared with those of Daidzein (DAI), a phytoestrogen, and of the female hormone estradiol (E2). In intact females, LEU disrupted the estrous cycle and female sexual behavior, decreased the number of follicles and corpora lutea, increased uterine and vaginal epithelium in proestrus and diestrus p...
Source: Physiology and Behavior - Category: Physiology Source Type: research
Publication date: Available online 15 September 2019Source: Advances in Biological RegulationAuthor(s): Yi Cai, Andrew Yousef, Jennifer R. Grandis, Daniel E. JohnsonAbstractEpidemiologic evidence indicates that regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) provides a protective effect against the development of colorectal, breast, and head and neck cancers. Genomic characterization of these cancers has lent considerable insight into the subpopulations of cancer patients who are most likely to benefit from NSAID therapy. The PIK3CA gene encodes the catalytic subunit of phosphatidylinositol 3-kinase (PI3K) and...
Source: Advances in Biological Regulation - Category: Biology Source Type: research
Publication date: Available online 15 September 2019Source: Advances in Biological RegulationAuthor(s): Samuel Gusscott, Francesco Tamiro, Vincenzo Giambra, Andrew P. WengAbstractT-cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer, characterized by an uncontrolled expansion and accumulation of T-cell progenitors. During leukemic progression, immature T cells grow abnormally and occupy the bone marrow compartment, thereby interfering with the production of normal blood cells. Pediatric T-ALL is curable with intensive chemotherapy, but there are significant, long-term side effects and ∼20% of patients suf...
Source: Advances in Biological Regulation - Category: Biology Source Type: research
Publication date: 25 November 2019Source: Journal of Industrial and Engineering Chemistry, Volume 79Author(s): Ramesh Duwa, Fakhrossadat Emami, Sooyeun Lee, Jee-Heon Jeong, Simmyung YookAbstractGlioblastoma multiforme (GBM) is the most aggressive, malignant brain tumor found in adults, and has a short median survival time (MST). GBM is a heterogeneous group of brain tumors, is highly prone to develop resistance and likely to recur. In the context of GBM, the delivery of anti-cancer drugs is challenging because the blood brain barrier (BBB) restricts the passage of small molecules. Currently, nanomedicines based on liposome...
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
Publication date: Available online 16 September 2019Source: European Polymer JournalAuthor(s): Maria Alice de Oliveira, Marina Guimarães Carvalho Machado, Sabrina Emanuelle Dias Silva, Thais Leite Nascimento, Eliana Martins Lima, Gwenaelle Pound-Lana, Vanessa Carla Furtado MosqueiraAbstractNear-infrared dyes are useful to monitor nanocarriers in vitro and in vivo and can serve as photosensitizers in cancer photodynamic therapy. However, strategies need to be developed to guarantee that the dye photophysical properties and loading within the drug delivery system remain stable for reliable tracking within biological s...
Source: European Polymer Journal - Category: Chemistry Source Type: research
Chem. Commun., 2019, Advance Article DOI: 10.1039/C9CC06418D, CommunicationMasayasu Kuwahara, Hiroto Fujita, Yuka Kataoka, Yasuyo Nakajima, Masanobu Yamada, Naoki Sugimoto Efficient anti-cancer drug condensation enabled equally inhibiting cell proliferation even at a concentration of 7.6 ± 0.36 nM, which was approximately 170-fold lower than the standard therapeutic concentrations of camptothecin (CPT) drugs. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
Conclusions75 IU of daily follitropin epsilon results in similar ovarian response as compared to a standard dose of 150 IU follitropin alfa. This dose could be tested in phase III.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
CONCLUSIONS In the transferred patients with a malignant cytology, preoperative US might be helpful to detect false-positive cytology cases. PMID: 31522188 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Abstract Rapid advance in oncology leads to increasing survival of oncologic patients. More and more of them live long enough to reach either the natural age of menopause or, as a side effect of their oncotherapy, experience the cessation of gonadal function, leading to premature ovarian insufficiency, with disturbing vasomotor symtoms and long-term negative cardiovascular and skeletal effects. Thus, an ever increasing number of cancer survivors search endocrinologic help in the form of hormone replacement therapy (HRT). The misinterpretation of the WHI (Women's Health Initiative) Study has lead to an irrational f...
Source: Pathology Oncology Research - Category: Pathology Authors: Tags: Pathol Oncol Res Source Type: research
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