Relationship of 18F-FDG PET/CT metabolic characteristics of primary lesion to tumor markers of lung cancer And their differences in clinical stages

Conclusions: Histopathologic subtypes have a significant influence on the relationship between primary metabolic parameters and tumor markers, also on their differences in clinical stages of lung cancer. AC with a higher primary MTV, TLG, serous CEA and CYFRA21-1 may have a higher risk of distant metastasis. Relationship of FDG metabolic characteristics to tumor markers of lung cancerDiameterSUVmaxMTVTLGPathological typesTumor Markersr valueP valuer valueP valuerP valuer valueP valueAdenocarcinomaCEA0.4490.0010.1690.2260.4520.0010.4220.002CYFRA21-10.4720.0000.2060.1390.4480.0010.4490.001Squamous carcinomaSCCA0.3500.0680.3430.0740.3560.0630.5040.006CYFRA21-10.5730.001-0.0590.7670.7000.0000.5440.003SCLCPro-GRP0.0360.2260.5160.0710.3460.2470.4340.138NSE0.4480.1240.1040.7340.5050.0780.5220.067CYFRA21-1-0.0170.9570.4620.1120.0001.0000.1870.541Differences in metabolic parameters and tumor markers between stage Ia~IIIa and IIIb~IVbDiameterSUVmaxMTVTLGCEACYFRA21-1SCCAPro-GRPNSEAdenocarcinomaU value164.500267.000112.500145.000114.500143.500P value0.0290.9040.0010.0100.0010.009Squamous carcinomaU value65.50086.00058.00066.00064.00062.000P value0.1400.5960.0690.1470.1230.102SCLCU value8.00010.0009.00010.00014.00012.0008.000P value0.1220.2170.1650.2170.5370.3550.123
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Lung Cancer Posters Source Type: research