Evaluation of the anti-PD-1 Flare Response in Patients with Advanced Melanoma Using FDG PET/CT Imaging and Hematologic Biomarkers

Conclusions: In patients with advanced melanoma, the immune response to anti-PD-1 therapy appears to occur early, with evidence of T cell reinvigoration in the blood at 1 week post-therapy; an associated flare response on FDG PET/CT imaging at 1 week post-therapy is predictive of a complete response to immunotherapy.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Chang, B., Huang, A., Shang, C., Palmer, K., Schubert, E., Xu, W., Amaravadi, R., Schuchter, L., Mitchell, T., Wherry, E., Farwell, M. Tags: Sarcoma/ Melanoma Posters Source Type: research