Increased Pituitary Uptake in Time of Flight Ga-68 DOTATATE Imaging. How Much is too Much and Does it Matter?

Conclusions: Normal pituitary SUVmax can be markedly increased on TOF DOTATATE PET imaging compared to previously reported normal ranges derived from non-TOF PET scanners. Furthermore, pituitary microadenomas are not associated with increased, but rather decreased DOTATATE uptake compared to normal pituitary. Additional imaging to investigate high DOTATATE activity in an anatomically normal sella is likely unwarranted.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Educational Exhibit Posters Source Type: research