18F-FDG PET/CT used for the diagnosis of polymyalgia rheumatica in patients of fever of unknown origin/inflammatory of unknown origin

In this study, we retrospectively analyzed data of a group FUO/IUO patients that suspected of PMR, aiming to analyze the imaging features of PMR in FDG PET/CT and evaluate the clinical value of FDG PET/CT in differential diagnosis of PMR. Materials and Methods: From January 2014 to June 2018, among the patients who underwent PET/CT examination because of FUO/IUO, 26 patients were suspected of PMR due to shoulder joint pain and stiffness, increased serum inflammatory factors and age over 50 years old. Clinical and imaging data of these 26 patients were retrospectively analyzed. Final diagnoses were made by board-certified rheumatologists. All patients underwent whole-body PET/CT acquisition from head to knee in the supine position with the arms next to the body.PET/CT images were interpreted visually, and the site of abnormal FDG uptake was recorded. Image characteristics of PMR were analyzed and image diagnostic criteria were proposed. According to the final clinical diagnosis, the diagnostic significance of PET/CT image diagnostic criteria and ACR 2012 classification criteria was compared. Results: Among the 26 patients, 10 cases were finally diagnosed as PMR. The remaining 16 cases were all connective tissue disease, including rheumatoid arthritis (5), dermatomyositis (3), ANCA-associated vasculitis (3), polyarteritis nodosa (2), RS3PE syndrome (1), relapsing polychondritis (1) and systemic panniculitis (1). FDG PET/CT imaging showed positive findings in all 26 patients. In...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Outcomes/Infectious Disease/Pulmonary Posters Source Type: research

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Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
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Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
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Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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