18F-FDG PET/CT used for the diagnosis of polymyalgia rheumatica in patients of fever of unknown origin/inflammatory of unknown origin
In this study, we retrospectively analyzed data of a group FUO/IUO patients that suspected of PMR, aiming to analyze the imaging features of PMR in FDG PET/CT and evaluate the clinical value of FDG PET/CT in differential diagnosis of PMR. Materials and Methods: From January 2014 to June 2018, among the patients who underwent PET/CT examination because of FUO/IUO, 26 patients were suspected of PMR due to shoulder joint pain and stiffness, increased serum inflammatory factors and age over 50 years old. Clinical and imaging data of these 26 patients were retrospectively analyzed. Final diagnoses were made by board-certified rheumatologists. All patients underwent whole-body PET/CT acquisition from head to knee in the supine position with the arms next to the body.PET/CT images were interpreted visually, and the site of abnormal FDG uptake was recorded. Image characteristics of PMR were analyzed and image diagnostic criteria were proposed. According to the final clinical diagnosis, the diagnostic significance of PET/CT image diagnostic criteria and ACR 2012 classification criteria was compared. Results: Among the 26 patients, 10 cases were finally diagnosed as PMR. The remaining 16 cases were all connective tissue disease, including rheumatoid arthritis (5), dermatomyositis (3), ANCA-associated vasculitis (3), polyarteritis nodosa (2), RS3PE syndrome (1), relapsing polychondritis (1) and systemic panniculitis (1). FDG PET/CT imaging showed positive findings in all 26 patients. In...
We describe the most highly recommended generic and disease-specific PRO tools in SCD and discuss the challenges of incorporating them in clinical practice. EXPERT OPINION: PRO measures are essential to incorporate into SCD clinical trials either as primary or secondary outcomes. The use of PRO measures in SCD facilitates a patient-centered approach, which is likely to lead to improved outcomes. Significant challenges remain in adapting PRO tools to routine clinical use and in developing countries. PMID: 33034214 [PubMed - as supplied by publisher]
Publication date: Available online 10 October 2020Source: Meta GeneAuthor(s): Mansour Zamanpoor, Hamid Ghaedi, Mir Davood Omrani
Currently in fellowship doing bread/butter procedures (MBB, epidurals, PNB, few SCS/PNS trials, etc.) and just interviewed at a private practice spot where they do a lot of procedures that I will have not done any training in prior to graduating (e.g. IT pump, SI fusion, Vertiflex, Kypho, MILD, Discectomy, lots of SCS/PNS trials etc) and significant amount of "OR pain procedures" at a very busy practice seeing 30-40 pts/day - how many of you are commonly performing these procedures and are... private practice concern
Publication date: October 2020Source: Brain, Behavior, and Immunity, Volume 89Author(s): Fernando Lopes, Fernando A. Vicentini, Nina L. Cluny, Alexander J. Mathews, Benjamin H. Lee, Wagdi A. Almishri, Lateece Griffin, William Gonçalves, Vanessa Pinho, Derek M. McKay, Simon A. Hirota, Mark G. Swain, Quentin J. Pittman, Keith A. Sharkey
BEST supplements to relieve joint pain: Is your arthritis playing up? The wetter and colder months could partially be to blame. These two pills may help.
Authors: Kim H, Lim YM, Lee EJ, Kim HW, Ahn HS, Kim KK PMID: 33029979 [PubMed]
CONCLUSIONS: More than half of the iIONP patients had an enhanced oculomotor nerve in MRI. A few of them also had elevated CSF IgG synthesis rate, but no further evidence for inflammation was found. The administration of steroids seemed to have no benefit other than increasing the blood glucose level. PMID: 33029972 [PubMed]
Publication date: Available online 10 October 2020Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Natália Freire Valente, Eliezer de Sousa Cardoso, Juliana Alencar da Silva Resende, Jeferson Antônio Santos
CONCLUSION: When gastroenterologists encounter NAFLD/NASH patients, serum CK should be verified. If hyperCKemia, frontal baldness, a hatched face, history of cataract surgery, and grip myotonia are noted, the possibility of MD may be considered. PMID: 33033573 [PubMed]
Authors: Kim MS, Moon JS, Kim MJ, Seong MW, Park SS, Ko JS Abstract Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by a mutation in the aldolase B gene. HFI patients exhibit nausea, vomiting, abdominal pain, hypoglycemia, and elevated liver enzymes after dietary fructose exposure. Chronic exposure might lead to failure to thrive, liver failure, renal failure, and, eventually, death. HFI usually manifests in infants when they are being weaned off of breastmilk. Because HFI has an excellent prognosis when patients maintain a strict restrictive diet, some patients remain undiagnosed du...