Staging of high-risk endometrial cancer with PET/CT and sentinel lymph node mapping.

Conclusions: PET/CT demonstrated high specificity (97.8%) in detecting pelvic LN metastases; its high positive predictive value can be useful to refer patients to appropriate debulking surgery. SLN biopsy and histological ultrastaging increased the identification of metastases (18.3%-25%) not detectable by PET/CT because of its spatial resolution, increasing false-negative PET/CT findings. The combination of both modalities seems promising for nodal staging purpose.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Crivellaro, C., Bonacina, M., De Bernardi, E., ELISEI, F., Adorni, M., Magni, S., Lamanna, M., Guerra, L., Buda, A., Landoni, C., Messa, C. Tags: Gynecological Cancers Source Type: research