18F-FCH PET/CT for patients with uremic hyperparathyroidism

Conclusion: The results of this study showed that 18F-FCH PET/CT was superior to US and MIBI in the preoperative diagnosis of uHPT, especially for lesions diagnosed as the thyroid nodule by US. Nevertheless, larger trials are needed in future to confirm the superiority of FCH PET/CT. Fig 1: Images in a 62-year-old woman with three parathyroid hyperplasia, the later 90 minute planar 99mTc-MIBI SPECT/CT image(a),the axial CT image (not shown) and fusion image(c) cannot present all three lesions clearly because of Hashimoto's thyroiditis. Although the planar 18F-FCH PET image (b) is a little messy because of renal osteopathy, the lesion is visible on the image(arrows). 18F-FCH PET/CT fusion image (d) show the homogeneous tracer uptake behind the left lobe of the thyroid gland(arrow).Fig 2: Images in a 61-year-old woman with multiple parathyroid hyperplasia, one with slightly ectopic (in the middle portion of the right thyroid gland) localization. US mistook it for a thyroid nodule (dotted circle) (b). The lesion is well delineated on the planar 18F-fluorocholine PET image (a) , the axial CT image (c) and PET/CT fusion image (d)(arrow).
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Thyroid and Para-Thyroid Source Type: research