Two stage {micro}PET/CT imaging of TCO-anti-CD11b with a64Cu-NOTA-tetrazine tracer to monitor anti-GBM and lupus nephritis
Conclusions: Anti-GBM and lupus nephritis were both successfully imaged by microPET/CT using a two-stage targeting strategy with the TCO-anti-CD11b/64Cu-NOTA-tetrazine system. Further studies are warranted to optimize these biorthogonal reactants for imaging and organ inflammation in autoimmune diseases. Key Words: CD11b, PET imaging, Copper-64, Pretargeting
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Xiong, C., Du, Y., Cao, Q., Alpay, M., Mohan, C., Li, C. Tags: Novel Radiochemistry for Cancer Applications Source Type: research
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