DSMA Renal Scan in Cardiac Amyloidosis

Systemic amyloidosis is a group of diseases that develops as the result of protein misfolding, formation, and deposition of amyloid into the organs.1 The organs involved depend, in part, on the type of amyloid and innate property of the individual proteins that remains incompletely understood. Patients with wild-type transthyretin (wtATTR) amyloidosis typically have predominately heart involvement, whereas those with mutant transthyretin (mATTR) amyloidosis have involvement of the heart, nerves, and eyes, while all organs except the brain can be involved in immunoglobulin light chain (AL) amyloidosis.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Editorial Source Type: research