Demonstrating suitability of the Caco ‐2 cell model for BCS‐based biowaiver according to the recent FDA and ICH harmonised guidelines

ConclusionsAssay standardisation assures the consistency of experimental data. Only such fully characterised model has the ability to accurately predict drug's intestinal permeability at the early stage of research or for the BCS ‐based biowaiver application.

Source: Journal of Pharmacy and Pharmacology - June 1, 2019 Category: Drugs & Pharmacology Authors: Tina Jarc, Ma ša Novak, Neli Hevir, Tea Lanišnik Rižner, Mateja Erdani Kreft, Katja Kristan Tags: Research Paper Source Type: research