Novel fluorescent sensors based on zinc(II) bis(dipyrromethenate)s for furosemide detection in organic media

Publication date: Available online 31 May 2019Source: Journal of Photochemistry and Photobiology A: ChemistryAuthor(s): Alexander A. Ksenofontov, Svetlana A. Stupikova, Pavel S. Bocharov, Mikhail M. Lukanov, Ksenia V. Ksenofontova, Ilya A. Khodov, Elena V. AntinaAbstractIn this paper, the sensitivity of new fluorescent sensors based on zinc(II) bis(dipyrromethenate)s ([Zn2L2]s) to the furosemide presence in organic media is described. It has been shown that the instantaneous spectral response of [Zn2L2]s to the furosemide presence is based on the fluorescence quenching effect. Multi-approach analysis (UV-vis and fluorescent titrations, PXRD, FTIR, 1H NMR, DOSY, and DFT calculations) has shown that the [Zn2L2]s fluorescence quenching is associated with the formation of stable [Zn2L2Fur]s supramolecular systems, capable of photoinduced electron transfer. The furosemide detection limit with using [Zn2L2]s was 65-78 μg·L-1. The proposed sensors can be used for the forensic, clinical and sports medicine needs.Graphical abstract
Source: Journal of Photochemistry and Photobiology A: Chemistry - Category: Chemistry Source Type: research