Prophylactic administration of glycoPEGylated factor IX provides protection and joint outcome superior to recombinant factor IX after induced joint bleeding.

CONCLUSIONS: These results indicate that, in comparison to rFIX, the prophylactic use of extended half-life FIX provides superior protection from bleeding-induced joint damage, manifested by improved correction of histologic parameters. This article is protected by copyright. All rights reserved. PMID: 31148392 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31148392?dopt=Abstract

Source: Thrombosis and Haemostasis - May 30, 2019 Category: Hematology Authors: Sun J, Livingston EW, Broberg ML, Johansen PB, Ley CD, Knudsen T, Ezban M, Bateman TA, Monahan PE, Taves S Tags: J Thromb Haemost Source Type: research