Many Feel 'Frozen' When Heart Attack Strikes

Title: Many Feel 'Frozen' When Heart Attack StrikesCategory: Health NewsCreated: 5/30/2019 12:00:00 AMLast Editorial Review: 5/31/2019 12:00:00 AM
Source: MedicineNet Heart General - Category: Cardiology Source Type: news

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These 2 ECGs were texted to me with the words " I think acute MI, but cardiology does not. "I believed these to be 2 serial ECGs:ECG 1: (later found to be time zero):Computer read: " minimal ST depression 0.025 mm "There is a small amount of STE in II, III, aVFFrom less than 0.5 mm - 0.5 mm.There is les than 0.5 mm of reciprocal ST depression in aVL, and an inverted T-waveAnd the other: (later found to be time 24 minutes):Now there is more STE and more STDOne very telling finding are the ST segments in V2-V6:ST depression has developed in V2-V6, downsloping in V4-V6.Though minimal, this is very specific...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
This study explored the possible protective activity of Skullcapflavone I (SF I), a flavonoid isolated from the root of Scutellaria baicalensis Georgi, on hypoxia-stimulated cardiomyocytes cell injury in vitro. Viability and apoptosis of H9c2 cells and primary cardiomyocytes were tested using cell counting kit-8 (CCK-8) assay and Guava Nexin Reagent, respectively. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used to measure the long non-coding RNA regulator of reprogramming (lincRNA-ROR) expression. si-ROR was transfected to knockdown lincRNA-ROR. Western blotting was conducted to assess the p...
Source: International Journal of Immunopathology and Pharmacology - Category: Allergy & Immunology Tags: Int J Immunopathol Pharmacol Source Type: research
ConclusionsA different role for the AGE-RAGE axis was observed in HF and ACS. All the sRAGE forms were directly related with glycation parameters in HF, but not in ACS. The independent value of the sRAGE forms on each cardiovascular disease was supported by esRAGE being an independent predictor of bad long-term prognosis only for HF.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
The U.S. Food and Drug Administration (FDA) has determined that recent data for rosiglitazone-containing drugs, such as Avandia, Avandamet, Avandaryl, and generics, do not show an increased risk of heart attack compared to the standard type 2 diabetes medicines metformin and sulfonylurea.
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
Publication date: Available online 21 June 2019Source: Canadian Journal of CardiologyAuthor(s): Mark Canney, Mila Tang, Lee Er, Sean J. Barbour, Ognjenka Djurdjev, Adeera Levin, CanPREDDICT InvestigatorsAbstractBackgroundUsing standard cut-offs derived from healthy adults, high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are frequently elevated in patients with reduced glomerular filtration rate (GFR), with unclear implications. We sought to compare GFR-specific cut-offs of each biomarker to standard cut-offs for discrimination of cardiovascular risk in asymptomatic pa...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ConclusionThe sleep quality of post myocardial infarction patients was poor and the prevalence of depression was low. There was no significant relationship between sleep quality or depression with re-infarction.
Source: International Journal of Nursing Sciences - Category: Nursing Source Type: research
Publication date: Available online 21 June 2019Source: American Heart JournalAuthor(s): Bernardete Weber, Ângela C Bersch-Ferreira, Camila R Torreglosa, Aline Marcadenti, Enilda S Lara, Jacqueline T da Silva, Rosana P Costa, Renato H N Santos, Otavio Berwanger, Rosa Bosquetti, Raira Pagano, Luis G S Mota, Juliana D de Oliveira, Rafael M Soares, Andrea P Galante, Suzana A da Silva, Fernando G Zampieri, Cristiane Kovacs, Fernanda C Amparo, Priscila MoreiraAbstractBackgroundAppropriate dietary recommendations represent a key part of secondary prevention in cardiovascular disease (CVD).ObjectiveWe evaluated the effective...
Source: American Heart Journal - Category: Cardiology Source Type: research
Written by Pendell MeyersHere are two striking examples from a single shift highlighting the fallibility of the standard " smiley face " or upwardly concave ST segment morphology " rule " .Case 1.Obvious STEMI and OMI with massive STE in the inferior and lateral leads, even extending back into V3. All STE has concave upward (smiley face) morphology. V2 shows STD indicating posterior involvement. V1 may be in a tug-of-war between STD from posterior involvement and STE from possible RV involvement. Reciprocal STD in I and aVL. Sinus bradycardia with first degree heart block present, cl...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
In this study, we evaluated whether patients undergoing PPCI both in-hours and out-of-hours experience similar care and clinical outcomes.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Original Article Source Type: research
ConclusionExogenous treatment of PGE2 and the EP4 receptor agonist blocked the pro-inflammatory actions of LPS. Mechanistically, this was mediated via reduced Akt phosphorylation and inhibition of NF-κB.
Source: Prostaglandins and Other Lipid Mediators - Category: Lipidology Source Type: research
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