Death for life: a path from apoptotic signaling to tissue-scale effects of apoptotic epithelial extrusion.

We describe how apoptosis can control epithelial homeostasis though epithelial extrusion, a highly orchestrated process based on high- order actomyosin structures and on the coordination between the apoptotic and the neighboring cells. Finally, we describe how the synergy among forces generated by multiple apoptotic cells can shape epithelia in embryo development.
PMID: 31143959 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Life Sciences : CMLS - May 28, 2019 Category: Cytology Authors: Gagliardi PA, Primo L Tags: Cell Mol Life Sci Source Type: research