Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil.

CONCLUSIONS: This is the first study to demonstrate the association between MBL2 haplotypes and dengue severity in Brazilians including adjustment for genetic ancestry. These results reinforce the role of mannose binding lectin in immune response to DENV. PMID: 31141020 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31141020?dopt=Abstract

Source: Memorias do Instituto Oswaldo Cruz - May 31, 2019 Category: Infectious Diseases Authors: Ornelas AMM, Xavier-de-Carvalho C, Alvarado-Arnez LE, Ribeiro-Alves M, Rossi ÁD, Tanuri A, de Aguiar RS, Moraes MO, Cardoso CC Tags: Mem Inst Oswaldo Cruz Source Type: research