Multimorbidity profile associated with disability among the elderly living in the Metropolitan Region of Belo Horizonte, Brazil

Resumo O objetivo foi investigar as associa ções da incapacidade em três níveis (ABVD, AIVD e mobilidade) com doenças cardiovasculares, diabetes e multimorbidade, entre idosos residentes na Região Metropolitana de Belo Horizonte (RMBH). Estudo transversal em amostra representativa de adultos da RMBH, tendo sido selecionados 2.172 idosos (60 anos ou mais). A incapacidade, para cada domínio (ABVD, AIVD e mobilidade), foi avaliada como o relato de muita dificuldade ou necessidade de ajuda para realizar pelo menos uma atividade entre as investigadas, e as doenças autorreferidas incluíram hipertensão arterial, infarto do miocárdio e angina, acidente vascular encefálico (AVE), diabetes, e as combinações dessas doenças. Utilizou-se regressão de Poisson ajustada, estimando-se também a fração atribuível populacional. Houve importante contribuição do AVE para a incapacidade em todos os domínios, com destaque para as A BVD, bem como do infarto/angina na incapacidade em AIVD e mobilidade, sobretudo quando combinadas com diabetes e hipertensão. O perfil de multimorbidade pode ser usado para identificação de grupos vulneráveis, que deveriam ser alvo de ações de prevenção e reabilitação, reduzindo o custo fi nanceiro e social desse evento entre idosos.Abstract The ...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research

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By WILLIAM H. BESTERMANN JR., MD New Scientific Breakthroughs Can Provide a Longer Healthier Life Twenty-one years of follow-up comparing usual care with a protocol-driven team-based intervention in diabetes proved that healthy life in humans can be prolonged by 8 years. These results were achieved at a lower per patient per year cost. Aging researchers have been confident that we will soon be able to prolong healthy life. This landmark study shows this ambitious goal can be achieved now with lifestyle intervention and a few highly effective proven medications. These medications interfere with the core molecular biol...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Medical Practice Patients aging chronic disease Denmark Diabetes William Bestermann Source Type: blogs
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Hongfei Gu1†, Shuang Shao2†, Jie Liu3,4,5, Zhenqian Fan2, Yu Chen2, Jingxian Ni3,4,5, Conglin Wang6, Jun Tu3,4,5, Xianjia Ning3,4,5, Yongzhong Lou1*, Bin Li1* and Jinghua Wang3,4,5* 1Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China 2Department of Endocrinology and Metabolism, The Second Hospital of Tianjin Medical University, Tianjin, China 3Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China 4Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China 5Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration i...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Disability adjusted life years (DALYs) are a statistical construct used in epidemiology to assess the harms caused by disease, particularly the chronic diseases of aging, as these are by far the greatest burden of disease that is inflicted upon the population as a whole. The costs of aging are huge, however they are measured. It is the greatest single cause of human suffering and death, and the economic effects of this constant destruction of human lives and capabilities are sized to match. The greatest good any of us can do in the world as it stands today is to work towards bringing aging under medical control. D...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
This study defines a new clinically relevant concept of T-cell senescence-mediated inflammatory responses in the pathophysiology of abnormal glucose homeostasis. We also found that T-cell senescence is associated with systemic inflammation and alters hepatic glucose homeostasis. The rational modulation of T-cell senescence would be a promising avenue for the treatment or prevention of diabetes. Intron Retention via Alternative Splicing as a Signature of Aging https://www.fightaging.org/archives/2019/03/intron-retention-via-alternative-splicing-as-a-signature-of-aging/ In recent years researchers have inv...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSIONS: In this prospective cohort study targeting community-dwelling older adults in Japan, less than 20 teeth was confirmed to be an independent risk factor for functional disability even after conducting propensity score matching. This study supports previous publications showing that oral health is associated with functional disability. PMID: 30686817 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
Smart belt for weight loss, spider-like walking car, terrifying Robo-Sharks, IoT cat toilet, the real version of the monolith from Space Odyssey: the world’s most famous tech circus brings the superlatives of innovation to Las Vegas every year. Here, we sorted out the most exciting, the less useful or the outright dumbest health technologies from CES 2019. The year of the solar cow What do power banks and cows have in common? The 2019 CES Innovation Award, actually. It’s a brilliant project of a South Korean solar energy company, Yolk, having partnered with a Kenyan educational institution, to keep children at...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine ces CES 2019 digital digital health digital health tech gadgets health technology health trends Innovation smartwatch summit wearables Source Type: blogs
In conclusion, we found a gradient of increasing blood pressure with higher levels of BMI. The fact that this gradient is present even in the fully adjusted analyses suggests that BMI may cause a direct effect on blood pressure, independent of other clinical risk factors. PRRX1 as a Possible Point of Control for Remyelination https://www.fightaging.org/archives/2018/12/prrx1-as-a-possible-point-of-control-for-remyelination/ Researchers here outline what is possibly a new point of intervention in the processes that maintain the myelin sheath that wraps nerves. This sheath is vital to the correct operatio...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: Overall, home based primary care seems to be a promising alternative for pts with SCD. It had a significant impact on patient quality of care and may improve prescription adherence, but more data are needed to determine if it has an effect on healthcare utilization for pts with SCD.DisclosuresMoore: Ohio State University College of Medicine: Research Funding. Desai: FDA: Research Funding; Pfizer: Research Funding; University of Pittsburgh: Research Funding; Selexy/Novartis: Research Funding; NIH: Research Funding; Ironwood: Other: Adjudication Committee.
Source: Blood - Category: Hematology Authors: Tags: 901. Health Services Research-Non-Malignant Conditions: Poster III Source Type: research
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