Severe and malignant hypertension are common in primary atypical hemolytic uremic syndrome
Malignant hypertension is listed among the causes of secondary thrombotic microangiopathy, but pathogenic mutations in complement genes have been reported in patients with hypertension-induced thrombotic microangiopathy. Here we investigated the frequency and severity of hypertension in 55 patients with primary atypical hemolytic uremic syndrome (aHUS). A genetic analysis was performed in all patients, and funduscopic examination was performed in all the patients with Grades 2 and 3 hypertension.
Source: Kidney International - Category: Urology & Nephrology Authors: Teresa Cavero, Emilia Arjona, Karina Soto, Fernando Caravaca-Font án, Cristina Rabasco, Luis Bravo, Francisco de la Cerda, Nadia Martín, Miquel Blasco, Ana Ávila, Ana Huerta, Virginia Cabello, Ana Jarque, Concepción Alcázar, Xavier Fulladosa, Javier Tags: Clinical Investigation Source Type: research
More News: Cancer & Oncology | Genetics | Hemolytic Uremic Syndrome (HUS) | Hypertension | Urology & Nephrology