Clinical Outcomes in Early Cervical Cancer Patients Treated with Nerve Plane–sparing Laparoscopic Radical Hysterectomy

Publication date: Available online 7 May 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Dan Zhao, Bin Li, Yating Wang, Shuanghuan Liu, Yanan Zhang, Guangwen YuanABSTRACTStudy ObjectiveTo explore the feasibility of nerve plane–sparing laparoscopic radical hysterectomy (NPS-LRH) as a simplified C1-type surgery for cervical cancer patients and to compare this technique with laparoscopic radical hysterectomy (LRH).DesignA retrospective comparative study.SettingAn academic tertiary hospital affiliated with the Chinese National Cancer Center.PatientsSix hundred fifteen patients with Fédération Internationale de Gynécologie et d'Obstétrique stage Ib and IIa cervical cancer who underwent laparoscopic radical hysterectomy between January 2010 and December 2017 were enrolled. Among them, 263 patients underwent the NPS-LRH surgery, and 352 patients underwent the LRH surgery. Intraoperative data and postoperative outcomes were compared between the 2 groups.InterventionsNPS-LRH is a simplified type C1 procedure that preserves the ureteral mesentery and its nerve plane, whereas LRH is a type C2 procedure in the Querleu-Morrow surgical classification system.Measurements and Main ResultsThere were no statistically significant differences in age, body mass index, Fédération Internationale de Gynécologie et d'Obstétrique stage, tumor differentiation, pathological type, depth of invasion, lymphovascular space invasion...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research

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Authors: Liu W, Zhou P, Chen K, Ye Z, Liu F, Li X, He N, Wu Z, Zhang Q, Gong X, Tang Q, Du X, Ying Y, Xu X, Zhang Y, Liu J, Li Y, Shen N, Couban RJ, Ibrahim QI, Guyatt G, Zhai S Abstract BACKGROUND: Antiviral medications are being given empirically to some patients with coronavirus disease 2019 (COVID-19). To support the development of a COVID-19 management guideline, we conducted a systematic review that addressed the benefits and harms of 7 antiviral treatments for COVID-19. METHODS: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), PubMed and 3 Chinese databases (CNKI, WA...
Source: Canadian Medical Association Journal - Category: General Medicine Tags: CMAJ Source Type: research
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Source: Current Radiopharmaceuticals - Category: Radiology Tags: Curr Radiopharm Source Type: research
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