US measles cases reach highest number in nearly three decades, CDC says
There have been 971 cases of measles reported in the United States this year, the US Centers for Disease Control and Prevention said Thursday.
CONCLUSIONS: Linking family assistance payments with childhood vaccination status and associated program improvements were followed by substantial catch-up vaccination activity, particularly in young people from families of lower socio-economic status. PMID: 32951230 [PubMed - as supplied by publisher]
We describe the clinical presentation and outcome of hospitalized patients during the outbreak.
r U Abstract Measles outbreaks occur rather frequently in Germany. Patients with chronic inflammatory diseases are often treated with immunosuppressants. A recent study showed that about 7% of such patients are not protected against measles according to the lack of documentation in the vaccination card or the absence of protective antibodies. The Standing Committee on Immunization (STIKO) recommends a first vaccination against measles as a measles-mumps-rubella combined vaccination (MMR) in children aged 11-14 months and a second vaccination at 14-23 months. For adults born after 1970, vaccination against measles ...
In this study, we evaluated age-specific susceptibility to four diseases in Khan Hoa province.
History illustrates the remarkable public health impact of mass vaccination, by dramatically improving life expectancy and reducing the burden of infectious diseases and co-morbidities worldwide. It has been perceived that if an individual adhered to the MMR vaccine schedule that immunity to mumps virus (MuV) would be lifelong. Recent mumps outbreaks in individuals who had received two doses of the Measles Mumps Rubella (MMR) vaccine has challenged the efficacy of the MMR vaccine. However, clinical symptoms, complications, viral shedding and transmission associated with mumps infection has been shown to be reduced in vacci...
Background: On 16th February 2018, District Health officer, Nasirabad reported 16 suspected measles cases from union council Dera Murad Jamali to provincial disease surveillance and response unit Quetta and requested for investigation. An FELTP fellow was deputed on 17th February to investigate outbreak, evaluate risk factors and recommend control measures.
Background: In 2000, endemic measles was declared eliminated in the US. However, a proliferation of anti-vaccination sentiment over the last decade has led to measles ’ re-emergence, with 2019 experiencing the most measles cases in the US since 1992. Rising rates of non-medical exemptions (NMEs) and low vaccination coverage in the state of Michigan prompted an administrative vaccine policy change in 2015, mandating that parents attend an in-person vaccine educa tion session prior to obtaining a non-medical exemption waiver.
Background: Despite the availability of safe and effective vaccines, measles resurgence has been observed worldwide in 2018 and 2019. In West Indian Ocean (WIO), almost all islands have reported measles cases during these years. Vaccine coverage was particularly low in Madagascar and Comoros Island, with a single dose provided by the Expanded Program on Immunization.
We describe a 2 year old boy with two previously undescribed frameshift mutations in the interferon (IFN)α/β receptor 2 (IFNAR2) gene presenting with hemophagocytic lymphohistiocytosis (HLH) following measles-mumps-rubella vaccination. Functional analyses show the absence of response to type I IFN in the patient’s cells, as revealed by the lack of phosphorylation of STAT1 and the lack of induction of interferon-stimulated genes upon ex vivo stimulation with IFNα. HLH has been reported in patients with inborn errors of type I IFN-mediated immune responses following vaccination with live-attenuated vir...
(American Chemical Society) Vaccines have curtailed the spread of several infectious diseases, such as smallpox, polio and measles. However, vaccines against some diseases, including HIV-1, influenza and malaria, don't work very well, and one reason could be the timing of antigen and adjuvant presentation to the immune system. Now, researchers reporting inACS Central Science developed an injectable hydrogel that allows sustained release of vaccine components, increasing the potency, quality and duration of immune responses in mice.